SCHEMBL15470916

SCHEMBL15470916

N#C/C(C(=O)c1ccccc1)=C1\c2ccccc2C(=O)c2c1ccc1ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.48
ALDH1A1 P00352 7/20 0.40
MAPT P10636 6/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
RAB9A P51151 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
LMNA P02545 3/20 0.38
ALOX15 P16050 2/20 0.38
HSD17B10 Q99714 2/20 0.38
HTT P42858 2/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
MAPK1 P28482 3/20 0.37
SOS1 Q07889 2/20 0.37
TSHR P16473 2/20 0.37
NSD2 O96028 1/20 0.37
OPRM1 P35372 1/20 0.37
OPRD1 P41143 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15470913 0.84 DNMT1 (0.51) DNMT1ALDH1A1MAPTMEN1KMT2A
SCHEMBL15470890 0.83 ALDH1A1 (0.51) ALDH1A1MAPTMEN1KMT2ARAB9A
SCHEMBL15470875 0.78 ALDH1A1 (0.56) ALDH1A1MAPTMEN1KMT2ARAB9A
SCHEMBL15600030 0.78 DNMT1 (0.48) DNMT1ALDH1A1MAPTMEN1KMT2A
SCHEMBL15470917 0.76 MAPT (0.47) DNMT1ALDH1A1MAPTMEN1KMT2A
SCHEMBL15600073 0.73 DNMT1 (0.51) DNMT1ALDH1A1MAPTMEN1KMT2A
SCHEMBL15470912 0.73 MAPT (0.49) DNMT1ALDH1A1MAPTMEN1KMT2A
SCHEMBL21938950 0.72 DNMT1 (0.56) DNMT1ALDH1A1MAPTMEN1KMT2A
SCHEMBL18863298 0.70 ALDH1A1 (0.44) ALDH1A1MAPTMEN1KMT2ARAB9A
SCHEMBL183078 0.70 DNMT1 (0.78) DNMT1ALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9926289-B2 Compositions, apparatus, systems, and methods for resolving electronic excited states BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2018-03-27 US disclosed
US-9926289-B2 Compositions, apparatus, systems, and methods for resolving electronic excited states BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2018-03-27 US disclosed
US-9765051-B2 Compositions, apparatus, systems, and methods for resolving electronic excited states HALLSTAR INNOVATIONS CORP. (US) 2017-09-19 US disclosed
US-9765051-B2 Compositions, apparatus, systems, and methods for resolving electronic excited states HALLSTAR INNOVATIONS CORP. (US) 2017-09-19 US disclosed
US-9650356-B2 2017-05-16 US disclosed
US-9650356-B2 2017-05-16 US disclosed
US-9611246-B2 Compositions, apparatus, systems, and methods for resolving electronic excited states HALLSTAR INNOVATIONS CORP. (US) 2017-04-04 US disclosed
US-9611246-B2 Compositions, apparatus, systems, and methods for resolving electronic excited states HALLSTAR INNOVATIONS CORP. (US) 2017-04-04 US disclosed
US-20160022555-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2016-01-28 US disclosed
US-20160022555-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2016-01-28 US disclosed
US-20160024046-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2016-01-28 US disclosed
US-20160024046-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2016-01-28 US disclosed
US-20160002200-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2016-01-07 US disclosed
US-20160002200-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2016-01-07 US disclosed
US-9145383-B2 Compositions, apparatus, systems, and methods for resolving electronic excited states HALLSTAR INNOVATIONS CORP. (US) 2015-09-29 US disclosed
US-9145383-B2 Compositions, apparatus, systems, and methods for resolving electronic excited states HALLSTAR INNOVATIONS CORP. (US) 2015-09-29 US disclosed
US-20140044654-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES HALLSTAR INNOVATIONS CORP. (US) 2014-02-13 US disclosed
US-20140044654-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES HALLSTAR INNOVATIONS CORP. (US) 2014-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160024046-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES RECQL, BLM, WRN DNMT1 409/4885ALDH1A1 734/4885MAPT 2772/4885
US-20160002200-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES RECQL, BLM, WRN DNMT1 409/4885ALDH1A1 734/4885MAPT 2772/4885
US-20140044654-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES RECQL, BLM, WRN DNMT1 409/4885ALDH1A1 734/4885MAPT 2772/4885
US-20160022555-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES RECQL, BLM, WRN DNMT1 409/4885ALDH1A1 734/4885MAPT 2772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.