Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.58 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.49 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.47 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.47 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL976287 | 0.87 | MALT1 (0.56) | MALT1SMPD1HDAC6HDAC1HDAC3 | |
| SCHEMBL15579547 | 0.86 | MALT1 (0.55) | MALT1SMPD1HDAC6HDAC1HDAC3 | |
| SCHEMBL15579544 | 0.86 | FAAH (0.53) | MALT1P2RY14MGLLABHD6SLC16A3 | |
| SCHEMBL15474332 | 0.81 | RPA1 (0.65) | MALT1SMPD1HDAC6HDAC1FAAH | |
| SCHEMBL30288595 | 0.80 | MALT1 (0.49) | MALT1P2RY14MGLLABHD6SLC16A3 | |
| SCHEMBL974118 | 0.79 | SLC16A3 (0.52) | MALT1SMPD1HDAC6HDAC1HDAC3 | |
| SCHEMBL3712001 | 0.75 | MALT1 (0.51) | MALT1SMPD1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL29606246 | 0.74 | HDAC6 (0.52) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL30288624 | 0.74 | MALT1 (0.49) | MALT1SMPD1MGLLABHD6 | |
| SCHEMBL26307120 | 0.74 | MALT1 (0.49) | MALT1SMPD1MGLLABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140045850-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140045850-A1 | INHIBITORS OF HISTONE DEACETYLASE | HDAC1, HDAC11, HDAC3 | MALT1 511/4885SMPD1 1060/4885HDAC6 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.