Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.87 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL502215 | 0.93 | HRH3 (1.00) | HRH3KCNH2 | |
| SCHEMBL502523 | 0.92 | HRH3 (1.00) | HRH3KCNH2ADRA1A | |
| SCHEMBL502360 | 0.91 | HRH3 (1.00) | HRH3KCNH2 | |
| SCHEMBL4473307 | 0.90 | HRH3 (0.96) | HRH3KCNH2ADRA1A | |
| SCHEMBL4472904 | 0.90 | HRH3 (1.00) | HRH3KCNH2 | |
| SCHEMBL2365281 | 0.85 | HRH3 (0.84) | HRH3KCNH2 | |
| SCHEMBL4462908 | 0.85 | HRH3 (1.00) | HRH3KCNH2 | |
| SCHEMBL2497609 | 0.84 | HRH3 (0.84) | HRH3KCNH2 | |
| SCHEMBL4469937 | 0.84 | HRH3 (0.80) | HRH3KCNH2 | |
| SCHEMBL4473357 | 0.83 | HRH3 (0.82) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2698157-A1 | Method of treatment using fatty acid synthesis inhibitors | Merck Sharp & Dohme Corp. (US) | 2014-02-19 | — | — | EP | disclosed |