Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL502064 | 0.92 | HRH3 (1.00) | HRH3KCNH2 | |
| SCHEMBL502215 | 0.92 | HRH3 (1.00) | HRH3KCNH2 | |
| SCHEMBL10476387 | 0.88 | HRH3 (0.90) | HRH3KCNH2 | |
| SCHEMBL502360 | 0.86 | HRH3 (1.00) | HRH3KCNH2 | |
| SCHEMBL2497609 | 0.85 | HRH3 (0.84) | HRH3KCNH2 | |
| SCHEMBL15475255 | 0.85 | HRH3 (0.87) | HRH3KCNH2 | |
| SCHEMBL4462908 | 0.84 | HRH3 (1.00) | HRH3KCNH2 | |
| SCHEMBL502383 | 0.83 | HRH3 (1.00) | HRH3KCNH2 | |
| SCHEMBL4467636 | 0.82 | HRH3 (1.00) | HRH3KCNH2 | |
| SCHEMBL4472663 | 0.82 | HRH3 (0.81) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348857-A1 | NOVEL CYCLIC BENZIMIDAZOLE DERIVATIVES USEFUL ANTI-DIABETIC AGENTS | Merck Sharp & Dohme Corp. (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010047982-A1 | NOVEL CYCLIC BENZIMIDAZOLE DERIVATIVES USEFUL ANTI-DIABETIC AGENTS | MERCK SHARP & DOHME CORP. (US) | 2010-04-29 | — | — | WO | disclosed |