Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11505320 | 0.83 | CYP2D6 (0.30) | CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6279256 | 0.81 | TSHR (0.41) | KDM4EATMCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6803983 | 0.81 | TSHR (0.41) | KDM4EATMCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL15475612 | 0.81 | TSHR (0.41) | KDM4EATMCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11172053 | 0.77 | KDM4E (0.39) | KDM4EATM | |
| SCHEMBL11172080 | 0.77 | KDM4E (0.39) | KDM4EATM | |
| SCHEMBL11172103 | 0.77 | KDM4E (0.39) | KDM4EATM | |
| SCHEMBL4835947 | 0.77 | TSHR (0.39) | — | |
| SCHEMBL10751146 | 0.74 | NPSR1 (0.34) | KDM4EATMCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6508196 | 0.71 | KDM4E (0.41) | KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2703407-B1 | METHOD FOR MANUFACTURING PHOSPHONOCROTONIC ACID DERIVATIVE | KOWA CO (JP) | 2017-07-26 | — | — | EP | disclosed |
| US-9540301-B2 | Method for manufacturing phosphonocrotonic acid derivative | KOWA COMPANY, LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| EP-2703407-A1 | METHOD FOR MANUFACTURING PHOSPHONOCROTONIC ACID DERIVATIVE | Kowa Company, Ltd. (JP) | 2014-03-05 | — | — | EP | disclosed |
| US-20140051876-A1 | METHOD FOR MANUFACTURING PHOSPHONOCROTONIC ACID DERIVATIVE | MANAC INCORPORATED (JP) | 2014-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140051876-A1 | METHOD FOR MANUFACTURING PHOSPHONOCROTONIC ACID DERIVATIVE | C1S, C3AR1, C9 | KDM4E 3719/4885ATM 2209/4885CYP2D6 237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.