SCHEMBL1548023

SCHEMBL1548023

C1=CC2CC1CC2COP(OCC1CC2C=CC1C2)OCC1CC2C=CC1C2

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.41
ALDH1A1 P00352 3/20 0.41
TSHR P16473 1/20 0.36
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11589797 0.84 KDM4E (0.39) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL257223 0.81 KDM4E (0.46) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL415514 0.80 KDM4E (0.44) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL414804 0.77 KDM4E (0.42) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL10709505 0.77 KDM4E (0.42) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL24796703 0.77 KDM4E (0.42) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL19689426 0.77 KDM4E (0.42) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL24183351 0.77 KDM4E (0.42) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL24183422 0.77 KDM4E (0.42) KDM4EALDH1A1TSHRMEN1KMT2A
SCHEMBL1716001 0.77 KDM4E (0.42) KDM4EALDH1A1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4090989-A CHLOROPRENE, CHLORINATED ISOBUTYLENE/ISOPRENE COPOLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-05-23 US claimed
US-4078022-A ANTIOZONANTS FOR CHLOROPRENE AND DIENE BLEND RUBBERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-03-07 US claimed
US-20160168505-A1 LUBRICANT COMPOSITIONS FOR TRANSMISSIONS TOTAL MARKETING SERVICES (FR) 2016-06-16 US disclosed
EP-3027719-A1 LUBRICANT COMPOSITIONS FOR TRANSMISSIONS Total Marketing Services (FR) 2016-06-08 EP disclosed
WO-2015014986-A1 LUBRICANT COMPOSITIONS FOR TRANSMISSIONS TOTAL MARKETING SERVICES (FR) 2015-02-05 WO disclosed
EP-2814918-A1 LUBRICATING COMPOSITIONS FOR TRANSMISSIONS Total Raffinage Marketing (FR) 2014-12-24 EP disclosed
WO-2013120965-A1 LUBRICATING COMPOSITIONS FOR TRANSMISSIONS TOTAL RAFFINAGE MARKETING (FR) 2013-08-22 WO disclosed
EP-2314661-A1 Lubricant and fuel compositions containing hydroxy polycarboxylic acid esters Chemtura Corporation (US) 2011-04-27 EP disclosed
EP-1740679-A2 LUBRICANT AND FUEL COMPOSITIONS CONTAINING HYDROXY POLYCARBOXYLIC ACID ESTERS CHEMTURA CORPORATION (US) 2007-01-10 EP disclosed
WO-2005087904-A2 LUBRICANT AND FUEL COMPOSITIONS CONTAINING HYDROXY POLYCARBOXYLIC ACID ESTERS CHEMTURA CORPORATION (US) 2005-09-22 WO disclosed
US-4235980-A NONFLAMMABLE MOLDING MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-11-25 US disclosed
US-4090989-A CHLOROPRENE, CHLORINATED ISOBUTYLENE/ISOPRENE COPOLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-05-23 US disclosed
US-4090989-A CHLOROPRENE, CHLORINATED ISOBUTYLENE/ISOPRENE COPOLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-05-23 US disclosed
US-4078022-A ANTIOZONANTS FOR CHLOROPRENE AND DIENE BLEND RUBBERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-03-07 US disclosed
US-4078022-A ANTIOZONANTS FOR CHLOROPRENE AND DIENE BLEND RUBBERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-03-07 US disclosed