⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinodihydroxamic Acid SCHEMBL940650 | 0.82 | FOLH1 (0.75) | — | |
| SCHEMBL2812551 | 0.78 | — | — | |
| SCHEMBL9547344 | 0.76 | — | — | |
| Glutarodihydroxamic Acid SCHEMBL11768782 | 0.76 | HDAC1 (0.81) | — | |
| SCHEMBL11768749 | 0.76 | HDAC1 (0.93) | — | |
| Suberohydroxamic Acid SCHEMBL2159033 | 0.73 | HDAC1 (1.00) | — | |
| SCHEMBL11767258 | 0.73 | HDAC1 (1.00) | — | |
| SCHEMBL11764904 | 0.73 | HDAC1 (1.00) | — | |
| SCHEMBL10439098 | 0.73 | HDAC1 (1.00) | — | |
| Azelaic Bis Hydroxamic Acid SCHEMBL4741072 | 0.73 | HDAC1 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170020874-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | CERENO SCIENT AB (SE) | 2017-01-26 | — | — | US | disclosed |
| US-20140051716-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | CERENO SCIENTIFIC AB | 2014-02-20 | — | — | US | disclosed |