Succinodihydroxamic Acid

Succinodihydroxamic Acid

SCHEMBL940650

O=C(CCC(=O)NO)NO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 3/20 0.75
▸ KDM4E B2RXH2 1/20 0.75
▸ KDM6B O15054 1/20 0.75
▸ KDM5C P41229 1/20 0.75
▸ EGLN1 Q9GZT9 1/20 0.75
▸ PHF8 Q9UPP1 1/20 0.75
▸ KDM2A Q9Y2K7 1/20 0.75
▸ HDAC1 Q13547 5/20 0.69
▸ HDAC2 Q92769 4/20 0.69
▸ HDAC8 Q9BY41 4/20 0.69
▸ HDAC6 Q9UBN7 4/20 0.69
▸ HDAC3 O15379 3/20 0.69
▸ HDAC5 Q9UQL6 2/20 0.69
▸ HSP90AA1 P07900 1/20 0.52
▸ ENO1 P06733 1/20 0.45
▸ ECE1 P42892 1/20 0.43
▸ ENPEP Q07075 1/20 0.42
▸ MMP1 P03956 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8638420 0.89 FOLH1 (0.63) FOLH1KDM4EKDM6BKDM5CEGLN1
SCHEMBL240068 0.87 — —
SCHEMBL11768749 0.85 HDAC1 (0.93) FOLH1KDM4EKDM6BKDM5CEGLN1
Glutarodihydroxamic Acid SCHEMBL11768782 0.85 HDAC1 (0.81) FOLH1KDM4EKDM6BKDM5CEGLN1
SCHEMBL27643837 0.84 FOLH1 (0.57) FOLH1KDM4EKDM6BKDM5CEGLN1
SCHEMBL137189 0.84 — —
SCHEMBL4572119 0.84 HDAC2 (0.57) FOLH1KDM4EKDM6BKDM5CEGLN1
SCHEMBL8249763 0.84 — —
SCHEMBL11769965 0.82 HDAC1 (1.00) FOLH1KDM4EKDM6BKDM5CEGLN1
Suberohydroxamic Acid SCHEMBL2159033 0.82 HDAC1 (1.00) FOLH1KDM4EKDM6BKDM5CEGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117264598-B Cobalt salt composite adhesive and preparation method thereof 江阴市三良橡塑新材料有限公司 2024-04-19 — — CN claimed
CN-117264598-A Cobalt salt composite adhesive and preparation method thereof 江阴市三良橡塑新材料有限公司 2023-12-22 — — CN claimed
EP-2691454-B1 CURABLE FLUOROELASTOMER COMPOSITION DU PONT (US) 2014-12-24 — — EP claimed
EP-2691454-A2 CURABLE FLUOROELASTOMER COMPOSITION E.I. Du Pont De Nemours And Company (US) 2014-02-05 — — EP claimed
US-8618222-B2 Curable fluoroelastomer composition E I DU PONT DE NEMOURS AND COMPANY (US) 2013-12-31 — — US claimed
US-20130066018-A1 CURABLE FLUOROELASTOMER COMPOSTION E I DU PONT DE NEMOURS AND COMPANY (US) 2013-03-14 — — US claimed
WO-2012135780-A2 CURABLE FLUOROELASTOMER COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-10-04 — — WO claimed
EP-1005449-B1 3-ARYL-SUCCINAMIDO-HYDROXAMIC ACIDS, METHODS FOR PRODUCING SAID ACIDS AND MEDICAMENTS CONTAINING THE SAME ROCHE DIAGNOSTICS GMBH (DE) 2002-10-30 — — EP claimed
EP-0944587-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1999-09-29 — — EP claimed
WO-1998024759-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1998-06-11 — — WO claimed
US-4939299-A Succinyl dihydroxamic acids MONSANTO COMPANY (US) 1990-07-03 — — US claimed
EP-0271468-A2 Gallium complexes and solvent extraction of gallium Monsanto Company (US) 1988-06-15 — — EP claimed
CN-117264598-B Cobalt salt composite adhesive and preparation method thereof 江阴市三良橡塑新材料有限公司 2024-04-19 — — CN disclosed
US-11865195-B2 Evaluation of presence of and vulnerability to atrial fibrillation and other indications using matrix metalloproteinase-based imaging LANTHEUS MEDICAL IMAGING, INC. (US) 2024-01-09 — — US disclosed
CN-117264598-A Cobalt salt composite adhesive and preparation method thereof 江阴市三良橡塑新材料有限公司 2023-12-22 — — CN disclosed
US-11653649-B2 Antimicrobial composition including a dihydroxamic acid and methods of inhibiting microbial growth utilizing the same KIMBERLY-CLARK WORLDWIDE, INC. (US) 2023-05-23 — — US disclosed
EP-0811019-A1 SYNTHESIS OF HYDROXAMIC ACID DERIVATIVES BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1997-12-10 — — EP disclosed
WO-1996026223-A1 SYNTHESIS OF HYDROXAMIC ACID DERIVATIVES BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1996-08-29 — — WO disclosed
US-4939299-A Succinyl dihydroxamic acids MONSANTO COMPANY (US) 1990-07-03 — — US disclosed
US-3979401-A Polyfunctional aliphatic and cycloaliphatic cyclic nitrile sulfites and carbonates ATLANTIC RICHFIELD COMPANY (US) 1976-09-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11653649-B2 Antimicrobial composition including a dihydroxamic acid and methods of inhibiting microbial growth utilizing the same DERA, DLD, DHODH FOLH1 2014/4885KDM4E 4682/4885KDM6B 4138/4885
US-11865195-B2 Evaluation of presence of and vulnerability to atrial fibrillation and other indications using matrix metalloproteinase-based imaging MMP3, MMP1, TIMP3 FOLH1 166/4885KDM4E 1930/4885KDM6B 1673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback