Succinodihydroxamic Acid

Succinodihydroxamic Acid

SCHEMBL940650

O=C(CCC(=O)NO)NO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.75
KDM4E B2RXH2 1/20 0.75
KDM6B O15054 1/20 0.75
KDM5C P41229 1/20 0.75
EGLN1 Q9GZT9 1/20 0.75
PHF8 Q9UPP1 1/20 0.75
KDM2A Q9Y2K7 1/20 0.75
HDAC1 Q13547 5/20 0.69
HDAC2 Q92769 4/20 0.69
HDAC8 Q9BY41 4/20 0.69
HDAC6 Q9UBN7 4/20 0.69
HDAC3 O15379 3/20 0.69
HDAC5 Q9UQL6 2/20 0.69
HSP90AA1 P07900 1/20 0.52
ENO1 P06733 1/20 0.45
ECE1 P42892 1/20 0.43
ENPEP Q07075 1/20 0.42
MMP1 P03956 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8638420 0.89 FOLH1 (0.63) FOLH1KDM4EKDM6BKDM5CEGLN1
SCHEMBL240068 0.87
Glutarodihydroxamic Acid SCHEMBL11768782 0.85 HDAC1 (0.81) FOLH1KDM4EKDM6BKDM5CEGLN1
SCHEMBL11768749 0.85 HDAC1 (0.93) FOLH1KDM4EKDM6BKDM5CEGLN1
SCHEMBL137189 0.84
SCHEMBL8249763 0.84
SCHEMBL27643837 0.84 FOLH1 (0.57) FOLH1KDM4EKDM6BKDM5CEGLN1
SCHEMBL4572119 0.84 HDAC2 (0.57) FOLH1KDM4EKDM6BKDM5CEGLN1
SCHEMBL11764904 0.82 HDAC1 (1.00) FOLH1KDM4EKDM6BKDM5CEGLN1
SCHEMBL10439098 0.82 HDAC1 (1.00) FOLH1KDM4EKDM6BKDM5CEGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117264598-B Cobalt salt composite adhesive and preparation method thereof 江阴市三良橡塑新材料有限公司 2024-04-19 CN claimed
CN-117264598-A Cobalt salt composite adhesive and preparation method thereof 江阴市三良橡塑新材料有限公司 2023-12-22 CN claimed
EP-2691454-B1 CURABLE FLUOROELASTOMER COMPOSITION DU PONT (US) 2014-12-24 EP claimed
EP-2691454-A2 CURABLE FLUOROELASTOMER COMPOSITION E.I. Du Pont De Nemours And Company (US) 2014-02-05 EP claimed
US-8618222-B2 Curable fluoroelastomer composition E I DU PONT DE NEMOURS AND COMPANY (US) 2013-12-31 US claimed
US-20130066018-A1 CURABLE FLUOROELASTOMER COMPOSTION E I DU PONT DE NEMOURS AND COMPANY (US) 2013-03-14 US claimed
WO-2012135780-A2 CURABLE FLUOROELASTOMER COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-10-04 WO claimed
EP-1005449-B1 3-ARYL-SUCCINAMIDO-HYDROXAMIC ACIDS, METHODS FOR PRODUCING SAID ACIDS AND MEDICAMENTS CONTAINING THE SAME ROCHE DIAGNOSTICS GMBH (DE) 2002-10-30 EP claimed
EP-0944587-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1999-09-29 EP claimed
WO-1998024759-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1998-06-11 WO claimed
US-4939299-A Succinyl dihydroxamic acids MONSANTO COMPANY (US) 1990-07-03 US claimed
EP-0271468-A2 Gallium complexes and solvent extraction of gallium Monsanto Company (US) 1988-06-15 EP claimed
CN-117264598-B Cobalt salt composite adhesive and preparation method thereof 江阴市三良橡塑新材料有限公司 2024-04-19 CN disclosed
US-11865195-B2 Evaluation of presence of and vulnerability to atrial fibrillation and other indications using matrix metalloproteinase-based imaging LANTHEUS MEDICAL IMAGING, INC. (US) 2024-01-09 US disclosed
CN-117264598-A Cobalt salt composite adhesive and preparation method thereof 江阴市三良橡塑新材料有限公司 2023-12-22 CN disclosed
US-11653649-B2 Antimicrobial composition including a dihydroxamic acid and methods of inhibiting microbial growth utilizing the same KIMBERLY-CLARK WORLDWIDE, INC. (US) 2023-05-23 US disclosed
EP-0811019-A1 SYNTHESIS OF HYDROXAMIC ACID DERIVATIVES BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1997-12-10 EP disclosed
WO-1996026223-A1 SYNTHESIS OF HYDROXAMIC ACID DERIVATIVES BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1996-08-29 WO disclosed
US-4939299-A Succinyl dihydroxamic acids MONSANTO COMPANY (US) 1990-07-03 US disclosed
US-3979401-A Polyfunctional aliphatic and cycloaliphatic cyclic nitrile sulfites and carbonates ATLANTIC RICHFIELD COMPANY (US) 1976-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11653649-B2 Antimicrobial composition including a dihydroxamic acid and methods of inhibiting microbial growth utilizing the same DERA, DLD, DHODH FOLH1 2014/4885KDM4E 4682/4885KDM6B 4138/4885
US-11865195-B2 Evaluation of presence of and vulnerability to atrial fibrillation and other indications using matrix metalloproteinase-based imaging MMP3, MMP1, TIMP3 FOLH1 166/4885KDM4E 1930/4885KDM6B 1673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.