Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 18/20 | 0.39 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10397271 | 0.72 | CYP19A1 (0.33) | CYP19A1 | |
| SCHEMBL290283 | 0.70 | ALDH1A1 (0.34) | CYP19A1 | |
| Hydrochloric Acid SCHEMBL23751428 | 0.68 | ALDH1A1 (0.33) | CYP19A1 | |
| Hydrochloric Acid SCHEMBL5805896 | 0.68 | ALDH1A1 (0.33) | CYP19A1 | |
| SCHEMBL1548048 | 0.68 | CYP19A1 (0.38) | CYP19A1SLC10A2 | |
| SCHEMBL11117357 | 0.67 | CYP2C9 (0.51) | SPHK1CYP19A1 | |
| SCHEMBL7752413 | 0.67 | CYP2C9 (0.51) | SPHK1CYP19A1 | |
| SCHEMBL11281432 | 0.66 | CYP19A1 (0.40) | CYP19A1 | |
| SCHEMBL7751373 | 0.66 | SPHK1 (0.51) | SPHK1CYP19A1 | |
| SCHEMBL7747021 | 0.66 | SPHK1 (0.51) | SPHK1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8632774-B2 | Antagonists of IL-6 | EMERGENT PRODUCT DEVELOPMENT SEATTLE, LLC (US) | 2014-01-21 | — | — | US | disclosed |
| US-20110177070-A1 | TGF-Beta Antagonist Multi-Target Binding Proteins | Emergent Product Development Seatlle, LLC | 2011-07-21 | — | — | US | disclosed |
| US-20110158995-A1 | Multi-Specific Binding Proteins Targeting B Cell Disorders | RENAULT S.A.S | 2011-06-30 | — | — | US | disclosed |
| US-20110152173-A1 | TNF-a ANTAGONIST MULTI-TARGET BINDING PROTEINS | Emergent Product Development Seattle ,LLC | 2011-06-23 | — | — | US | disclosed |
| US-20110142851-A1 | IL6 Immunotherapeutics | TRUBION PHARMACEUTICALS, INC. | 2011-06-16 | — | — | US | disclosed |
| EP-2321345-A1 | MULTI-SPECIFIC BINDING PROTEINS TARGETING B CELL DISORDERS | Emergent Product Development Seattle, LLC (US) | 2011-05-18 | — | — | EP | disclosed |
| EP-2313109-A2 | IL6 IMMUNOTHERAPEUTICS | Emergent Product Development Seattle, LLC (US) | 2011-04-27 | — | — | EP | disclosed |
| EP-2310410-A2 | TNF- ANTAGONIST MULTI-TARGET BINDING PROTEINS | Emergent Product Development Seattle, LLC (US) | 2011-04-20 | — | — | EP | disclosed |
| EP-2310508-A1 | TGF-B ANTAGONIST MULTI-TARGET BINDING PROTEINS | Emergent Product Development Seattle, LLC (US) | 2011-04-20 | — | — | EP | disclosed |
| WO-2010014629-A1 | MULTI-SPECIFIC BINDING PROTEINS TARGETING B CELL DISORDERS | TRUBION PHARMACEUTICALS, INC. (US) | 2010-02-04 | — | — | WO | disclosed |
| WO-2010003108-A2 | TNF-α ANTAGONIST MULTI-TARGET BINDING PROTEINS | TRUBION PHARMACEUTICALS, INC. (US) | 2010-01-07 | — | — | WO | disclosed |
| WO-2010003101-A2 | IL6 IMMUNOTHERAPEUTICS | TRUBION PHARMACEUTICALS, INC. (US) | 2010-01-07 | — | — | WO | disclosed |
| WO-2010003118-A1 | TGF-B ANTAGONIST MULTI-TARGET BINDING PROTEINS | TRUBION PHARMACEUTICALS, INC. (US) | 2010-01-07 | — | — | WO | disclosed |