Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 8/20 | 0.43 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | GALK1 | P51570 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12831073 | 0.93 | ANO1 (0.43) | DHODHANO1ANO2THRBDAGLA | |
| SCHEMBL12830017 | 0.86 | KDM4E (0.45) | ANO1 | |
| SCHEMBL12831071 | 0.86 | MAPT (0.43) | ANO1THRBLMNA | |
| SCHEMBL12830946 | 0.86 | THRB (0.40) | DHODHANO1ANO2THRBLMNA | |
| SCHEMBL1954005 | 0.83 | ANO1 (0.64) | ANO1ANO2 | |
| SCHEMBL12830947 | 0.83 | ANO1 (0.45) | DHODHANO1HDAC6KDR | |
| SCHEMBL12756319 | 0.81 | ANO1 (0.38) | ANO1ANO2THRBDAGLA | |
| SCHEMBL12756363 | 0.81 | ANO1 (0.39) | DHODHANO1ANO2THRB | |
| SCHEMBL12830945 | 0.81 | TP53 (0.45) | DHODHANO1THRBLMNAHDAC6 | |
| SCHEMBL12831052 | 0.81 | GALK1 (0.37) | DHODHTHRBDAGLALMNAGALK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140051711-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2014-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140051711-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | ORAI1, SARAF, RYR2 | DHODH 2153/4885ANO1 114/4885ANO2 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.