SCHEMBL15499124

SCHEMBL15499124

CCC(C)(C)C(=O)Oc1ccc(C(C)(c2ccccc2)c2ccc(OC(C)C)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
KMT2A Q03164 3/20 0.45
ALDH1A1 P00352 3/20 0.45
MEN1 O00255 2/20 0.45
GAA P10253 2/20 0.45
LMNA P02545 1/20 0.45
TP53 P04637 1/20 0.45
ELANE P08246 4/20 0.41
NR1H4 Q96RI1 1/20 0.41
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
KDM4E B2RXH2 2/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 2/20 0.40
CNR2 P34972 1/20 0.40
MAPT P10636 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PTPN5 P54829 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18135085 0.88 ELANE (0.50) NPC1RAB9AKMT2AALDH1A1MEN1
SCHEMBL16160660 0.87 ELANE (0.44) NPC1RAB9AKMT2AALDH1A1MEN1
SCHEMBL13191439 0.85 ELANE (0.47) NPC1RAB9AKMT2AALDH1A1MEN1
SCHEMBL13764947 0.84 ELANE (0.47) NPC1RAB9AKMT2AALDH1A1MEN1
SCHEMBL13063797 0.83 ELANE (0.42) RAB9AKMT2AALDH1A1MEN1GAA
SCHEMBL15497373 0.82 MAPT (0.50) RAB9AKMT2AALDH1A1MEN1GAA
SCHEMBL14679479 0.81 ELANE (0.47) RAB9AKMT2AALDH1A1MEN1GAA
SCHEMBL13765242 0.81 ELANE (0.45) NPC1RAB9AKMT2AALDH1A1MEN1
SCHEMBL21942675 0.81 ELANE (0.54) NPC1RAB9AKMT2AALDH1A1MEN1
SCHEMBL24098475 0.81 MAPT (0.42) NPC1RAB9AKMT2AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140065532-A1 CHARGE TRANSPORT SUBSTANCE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2014-03-06 US disclosed