Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 19/20 | 0.75 |
| ▸ | CA2 | P00918 | 19/20 | 0.75 |
| ▸ | CA4 | P22748 | 10/20 | 0.75 |
| ▸ | CA12 | O43570 | 4/20 | 0.75 |
| ▸ | CA9 | Q16790 | 4/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4268752 | 0.93 | CA1 (0.67) | CA1CA2CA4CA12CA9 | |
| SCHEMBL4272357 | 0.93 | CA1 (0.67) | CA1CA2CA4CA12CA9 | |
| SCHEMBL13523700 | 0.92 | CA1 (0.66) | CA1CA2CA4CA12CA9 | |
| SCHEMBL19663826 | 0.92 | CA1 (0.70) | CA1CA2CA4CA12CA9 | |
| SCHEMBL6047697 | 0.91 | CA1 (0.64) | CA1CA2CA4CA12CA9 | |
| SCHEMBL13523712 | 0.86 | CA1 (0.60) | CA1CA2CA4CA12CA9 | |
| SCHEMBL13523716 | 0.85 | CA1 (0.59) | CA1CA2CA4CA12CA9 | |
| SCHEMBL6047699 | 0.85 | CA1 (0.59) | CA1CA2CA4CA12CA9 | |
| SCHEMBL4365925 | 0.85 | HDAC1 (0.65) | CA1CA2CA4CA12CA9 | |
| SCHEMBL19370390 | 0.85 | CA1 (1.00) | CA1CA2CA4CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140065075-A1 | TARGETED CONTRAST AGENTS AND USES THEREOF | RF THERAPEUTICS INC. (CA) | 2014-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140065075-A1 | TARGETED CONTRAST AGENTS AND USES THEREOF | ANTXR2, CALCOCO2, PAICS | CA1 89/4885CA2 88/4885CA4 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.