Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 18/20 | 0.67 |
| ▸ | CA2 | P00918 | 18/20 | 0.67 |
| ▸ | CA4 | P22748 | 7/20 | 0.67 |
| ▸ | CA12 | O43570 | 4/20 | 0.67 |
| ▸ | CA9 | Q16790 | 4/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4272357 | 1.00 | CA1 (0.67) | CA1CA2CA4CA12CA9 | |
| SCHEMBL15499792 | 0.93 | CA1 (0.75) | CA1CA2CA4CA12CA9 | |
| SCHEMBL4365925 | 0.93 | HDAC1 (0.65) | CA1CA2CA4CA12CA9 | |
| SCHEMBL9974560 | 0.91 | CA1 (0.64) | CA1CA2CA4CA12CA9 | |
| SCHEMBL23135490 | 0.86 | CA1 (0.53) | CA1CA2CA4CA12CA9 | |
| SCHEMBL9170624 | 0.86 | CA1 (0.53) | CA1CA2CA4CA12CA9 | |
| SCHEMBL13523700 | 0.85 | CA1 (0.66) | CA1CA2CA4CA12CA9 | |
| SCHEMBL19663826 | 0.85 | CA1 (0.70) | CA1CA2CA4CA12CA9 | |
| SCHEMBL9639810 | 0.85 | HDAC1 (0.59) | CA1CA2HDAC1KDM4ETSHR | |
| SCHEMBL5310831 | 0.84 | HDAC1 (0.56) | CA1CA2CA4CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605146-B2 | Process for producing an amide compound | NIHON MEDI-PHYSICS COMPANY, LIMITED (JP) | 2009-10-20 | — | — | US | claimed |
| EP-1199312-A2 | Process for producing an amide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-04-24 | — | — | EP | claimed |
| EP-0413405-A2 | Use of amide complex compounds | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-02-20 | — | — | EP | claimed |
| US-7605146-B2 | Process for producing an amide compound | NIHON MEDI-PHYSICS COMPANY, LIMITED (JP) | 2009-10-20 | — | — | US | disclosed |
| EP-1199312-A2 | Process for producing an amide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-04-24 | — | — | EP | disclosed |
| EP-0413405-A2 | Use of amide complex compounds | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-02-20 | — | — | EP | disclosed |