Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 17/20 | 0.77 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | THRA | P10827 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | LIG1 | P18858 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3,5-Diiodothyropropionic Acid SCHEMBL1501771 | 0.87 | PCNA (1.00) | PCNAPOLBTHRATHRBHIF1A | |
| SCHEMBL12642750 | 0.86 | PCNA (0.74) | PCNAPOLBTHRATHRBHIF1A | |
| SCHEMBL16126006 | 0.85 | PCNA (1.00) | PCNAPOLBTHRATHRBHIF1A | |
| SCHEMBL16124469 | 0.84 | PCNA (0.55) | PCNATHRATHRBLMNACYP1A2 | |
| SCHEMBL14264010 | 0.82 | PCNA (0.67) | PCNAPOLBTHRATHRBHIF1A | |
| SCHEMBL19663420 | 0.81 | PCNA (0.82) | PCNAPOLBTHRATHRBHIF1A | |
| SCHEMBL16124470 | 0.81 | PCNA (0.82) | PCNAPOLBTHRATHRBHIF1A | |
| SCHEMBL14485269 | 0.81 | PCNA (0.74) | PCNAPOLBTHRATHRBHIF1A | |
| SCHEMBL14485275 | 0.80 | PCNA (1.00) | PCNAPOLBTHRATHRBHIF1A | |
| SCHEMBL16124480 | 0.80 | PCNA (0.63) | PCNALIG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8668926-B1 | Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations thereof | NANOPHARMACEUTICALS LLC | 2014-03-11 | — | — | US | disclosed |
| US-8668926-B1 | Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations thereof | NANOPHARMACEUTICALS LLC | 2014-03-11 | — | — | US | disclosed |