Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | SLC1A5 | Q15758 | 9/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13233388 | 1.00 | ARG1 (0.50) | ARG1DPP8DPP9DPP7FPR2 | |
| SCHEMBL2838808 | 1.00 | ARG1 (0.50) | ARG1DPP8DPP9DPP7FPR2 | |
| SCHEMBL13233375 | 0.92 | ARG1 (0.49) | ARG1DPP8DPP9DPP7SLC1A5 | |
| SCHEMBL13263667 | 0.88 | ARG1 (0.40) | ARG1DPP8DPP9DPP7FPR2 | |
| SCHEMBL13233376 | 0.87 | ARG1 (0.52) | ARG1DPP8DPP9DPP7SLC1A5 | |
| SCHEMBL13263990 | 0.86 | ARG1 (0.51) | ARG1DPP8DPP9DPP7SLC1A5 | |
| SCHEMBL1741937 | 0.85 | ARG1 (0.43) | ARG1DPP8DPP9DPP7FPR2 | |
| SCHEMBL1741941 | 0.85 | ARG1 (0.43) | ARG1DPP8DPP9DPP7FPR2 | |
| SCHEMBL2504723 | 0.83 | ARG1 (0.46) | ARG1DPP8DPP9DPP7SLC1A5 | |
| SCHEMBL15834883 | 0.83 | ARG1 (0.46) | ARG1DPP8DPP9DPP7SLC1A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2706057-B1 | Bis(imidazolyl)compounds and radionuclide complexes | MOLECULAR INSIGHT PHARM INC (US) | 2016-04-20 | — | — | EP | disclosed |
| EP-2706057-A1 | Bis(imidazolyl)compounds and radionuclide complexes | Molecular Insight Pharmaceuticals, Inc. (US) | 2014-03-12 | — | — | EP | disclosed |