Butylscopolamine

Butylscopolamine

SCHEMBL155102

CCCC[N+]1(C)C2CC(OC(=O)C(CO)c3ccccc3)CC1C1OC12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 7/20 1.00
CHRM1 P11229 5/20 1.00
BLM P54132 4/20 1.00
TSHR P16473 4/20 1.00
PMP22 Q01453 2/20 1.00
CYP2D6 P10635 1/20 1.00
KCNH2 Q12809 1/20 1.00
LMNA P02545 2/20 0.98
CHRM5 P08912 5/20 0.76
CHRM4 P08173 3/20 0.75
CHRM3 P20309 3/20 0.75
HIF1A Q16665 2/20 0.75
CYP3A4 P08684 1/20 0.75
CYP2C9 P11712 1/20 0.75
HSD17B10 Q99714 1/20 0.75
SMN1; SMN2 Q16637 1/20 0.68
CYP1A2 P05177 1/20 0.61
NFKB1 P19838 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butylscopolamine SCHEMBL29643439 1.00 CHRM2 (1.00) CHRM2CHRM1BLMTSHRPMP22
Butylscopolamine SCHEMBL2446872 1.00 CHRM2 (1.00) CHRM2CHRM1BLMTSHRPMP22
Butylscopolamine SCHEMBL2446869 1.00 CHRM2 (1.00) CHRM2CHRM1BLMTSHRPMP22
Butylscopolamine SCHEMBL29473416 1.00 CHRM2 (1.00) CHRM2CHRM1BLMTSHRPMP22
Butylscopolamine SCHEMBL14672547 1.00 CHRM2 (1.00) CHRM2CHRM1BLMTSHRPMP22
Butylscopolamine SCHEMBL16168163 1.00 CHRM2 (1.00) CHRM2CHRM1BLMTSHRPMP22
Butylscopolamine SCHEMBL25292 0.99 BLM (1.00) CHRM2CHRM1BLMTSHRPMP22
Butylscopolamine SCHEMBL25291 0.99 BLM (1.00) CHRM2CHRM1BLMTSHRPMP22
Butylscopolamine SCHEMBL2441812 0.99 BLM (1.00) CHRM2CHRM1BLMTSHRPMP22
Butylscopolamine SCHEMBL10732357 0.99 CHRM2 (0.98) CHRM2CHRM1BLMTSHRPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12480131-B2 Tropane alkaloid (TA) producing non-plant host cells, and methods of making and using the same THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-11-25 US claimed
CN-113784758-B Non-plant host cells producing tropane alkaloids (TA) and methods of making and using the same 小利兰·斯坦福大学托管委员会 2025-03-07 CN claimed
US-20240191267-A1 Tropane Alkaloid Transporters and Methods of Making Tropane Alkaloids Using the Same HERCULES CAPITAL, INC., AS AGENT 2024-06-13 US claimed
EP-4314301-A1 TROPANE ALKALOID TRANSPORTERS AND METHODS OF MAKING TROPANE ALKALOIDS USING THE SAME The Board of Trustees of the Leland Stanford Junior University (US) 2024-02-07 EP claimed
WO-2022204283-A1 TROPANE ALKALOID TRANSPORTERS AND METHODS OF MAKING TROPANE ALKALOIDS USING THE SAME THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2022-09-29 WO claimed
US-20220170026-A1 TROPANE ALKALOID (TA) PRODUCING NON-PLANT HOST CELLS, AND METHODS OF MAKING AND USING THE SAME HERCULES CAPITAL, INC., AS AGENT 2022-06-02 US claimed
EP-3934765-A1 TROPANE ALKALOID (TA) PRODUCING NON-PLANT HOST CELLS, AND METHODS OF MAKING AND USING THE SAME The Board Of Trustees Of The Leland Stanford Junior University (US) 2022-01-12 EP claimed
WO-2020185626-A1 TROPANE ALKALOID (TA) PRODUCING NON-PLANT HOST CELLS, AND METHODS OF MAKING AND USING THE SAME THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2020-09-17 WO claimed
EP-1014943-B1 MEDICAL AEROSOL FORMULATIONS JAGO RES AG (CH) 2002-06-19 EP claimed
EP-0711292-B1 AZA SPIRO COMPOUNDS ACTING ON THE CHOLINERGIC SYSTEM WITH MUSCARINIC AGONIST ACTIVITY KOSM GERALD EMMANUEL (GB) 2002-01-23 EP claimed
WO-1995003303-A2 AZA SPIRO COMPOUNDS ACTING ON THE CHOLINERGIC SYSTEM WITH MUSCARINIC AGONIST ACTIVITY STATE OF ISRAEL, REPRESENTED BY THE PRIME MINISTER'S OFFICE, ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) 1995-02-02 WO claimed
US-5106831-A Cholinergic agent STATE OF ISRAEL, REPRESENTED BY THE PRIME MINISTER'S OFFICE, ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) 1992-04-21 US claimed
EP-0452101-A2 Spiro bridged and unbridged heterocyclic compounds ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) 1991-10-16 EP claimed
US-5053412-A Central nervous system disorders ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) 1991-10-01 US claimed
EP-0304730-B1 MEDICAMENTS CONTAINING N-ALKYL SCOPOL AMINE SALT AND NITROGLYCERINE, METHOD FOR ITS PREPARATION AND ITS USE G. Pohl-Boskamp GmbH & Co. Chemisch-pharmazeutische Fabrik (DE) 1991-06-26 EP claimed
US-4876260-A NERVOUS SYSTEM DISORDERS STATE OF ISRAEL, ISRAEL INSTITUTE OF BIOLOGICAL RESEARCH (IL) 1989-10-24 US claimed
EP-0193056-B1 COMBINATION OF FLUPIRTIN WITH SPASMOLYTICS HAVING AN ANTICHOLINERGIC EFFECT ASTA Pharma Aktiengesellschaft (DE) 1989-06-07 EP claimed
EP-0314444-A2 Novel oxathiolanes and derivatives thereof, pharmaceutical compositions containing them and the use thereof as medicaments State of IsraelRepresented by the Prime Minister's OfficeThe Israel Institute for Biological Research (IL) 1989-05-03 EP claimed
EP-0303391-A2 Optical isomers of a spiroquinuclidine derivative State of IsraelRepresented by the Prime Minister's OfficeThe Israel Institute for Biological Research (IL) 1989-02-15 EP claimed
US-4668684-A Combination of flupirtin and anticholinergic acting spasmolytic DEGUSSA AKTIENGESELLSCHAFT (DE) 1987-05-26 US claimed