Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 7/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 5/20 | 1.00 |
| ▸ | BLM | P54132 | 4/20 | 1.00 |
| ▸ | TSHR | P16473 | 4/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.98 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.76 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.75 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butylscopolamine SCHEMBL29643439 | 1.00 | CHRM2 (1.00) | CHRM2CHRM1BLMTSHRPMP22 | |
| Butylscopolamine SCHEMBL2446872 | 1.00 | CHRM2 (1.00) | CHRM2CHRM1BLMTSHRPMP22 | |
| Butylscopolamine SCHEMBL2446869 | 1.00 | CHRM2 (1.00) | CHRM2CHRM1BLMTSHRPMP22 | |
| Butylscopolamine SCHEMBL29473416 | 1.00 | CHRM2 (1.00) | CHRM2CHRM1BLMTSHRPMP22 | |
| Butylscopolamine SCHEMBL14672547 | 1.00 | CHRM2 (1.00) | CHRM2CHRM1BLMTSHRPMP22 | |
| Butylscopolamine SCHEMBL155102 | 1.00 | CHRM2 (1.00) | CHRM2CHRM1BLMTSHRPMP22 | |
| Butylscopolamine SCHEMBL25292 | 0.99 | BLM (1.00) | CHRM2CHRM1BLMTSHRPMP22 | |
| Butylscopolamine SCHEMBL25291 | 0.99 | BLM (1.00) | CHRM2CHRM1BLMTSHRPMP22 | |
| Butylscopolamine SCHEMBL2441812 | 0.99 | BLM (1.00) | CHRM2CHRM1BLMTSHRPMP22 | |
| Butylscopolamine SCHEMBL10732357 | 0.99 | CHRM2 (0.98) | CHRM2CHRM1BLMTSHRPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9707220-B2 | Scopolamine for the treatment of depression and anxiety | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2017-07-18 | — | — | US | disclosed |
| US-20140378501-A1 | SCOPOLAMINE FOR THE TREATMENT OF DEPRESSION AND ANXIETY | The Governmen of the United States of America, as represented by Secretary, Department of Health and (US) | 2014-12-25 | — | — | US | disclosed |
| US-8859585-B2 | Scopolamine for the treatment of depression and anxiety | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2014-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378501-A1 | SCOPOLAMINE FOR THE TREATMENT OF DEPRESSION AND ANXIETY | CHRNA1, CHRNA2, SLC18A3 | CHRM2 9/4885CHRM1 5/4885BLM 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.