Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | C1R | P00736 | 2/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1957000 | 0.86 | CYP2A6 (0.48) | CYP2A6ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL30805630 | 0.86 | CYP2A6 (0.48) | CYP2A6ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL15511865 | 0.86 | ALDH1A1 (0.43) | CYP2A6ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL31037118 | 0.77 | RXFP1 (0.39) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL1933388 | 0.77 | RXFP1 (0.39) | ALDH1A1KDM4EGAAMEN1MAPT | |
| SCHEMBL28118837 | 0.74 | POLB (0.47) | CYP2A6HSD17B10MEN1KMT2ACYP1A2 | |
| SCHEMBL21360526 | 0.74 | CYP1A2 (0.44) | CYP2A6ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL28097996 | 0.74 | ALDH1A1 (0.43) | CYP2A6ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL734973 | 0.72 | CYP2A6 (0.44) | CYP2A6ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL28769250 | 0.71 | HSP90AA1 (0.38) | CYP2A6ALDH1A1MEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9481618-B2 | Cyclopolyarylene compound and method of manufacturing same | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2016-11-01 | — | — | US | disclosed |
| CN-103415495-B | Ring polyarylene compounds and preparation method thereof | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-09-02 | — | — | CN | disclosed |
| US-20140066661-A1 | CYCLOPOLYARYLENE COMPOUND AND METHOD OF MANUFACTURING SAME | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140066661-A1 | CYCLOPOLYARYLENE COMPOUND AND METHOD OF MANUFACTURING SAME | CYP1B1, CYP51A1, CYP1A1 | CYP2A6 60/4885ALDH1A1 166/4885HIF1A 2487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.