Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPRF | P10586 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1277232 | 0.87 | — | — | |
| SCHEMBL19547128 | 0.76 | PSMB5 (0.34) | PTPN1PTPRCPTPRFCDC25BLMNA | |
| Hydrochloric Acid SCHEMBL15512413 | 0.75 | PSMB5 (0.33) | PTPN1PTPRCPTPRFCDC25BLMNA | |
| SCHEMBL15512414 | 0.72 | PSMB5 (0.32) | PTPN1PTPRCPTPRFCDC25BPSMB5 | |
| SCHEMBL4454087 | 0.66 | — | — | |
| SCHEMBL1316463 | 0.64 | KDR (0.52) | PSMB5 | |
| SCHEMBL27925078 | 0.64 | PSMB5 (0.33) | PTPN1PTPRCPTPRFCDC25BLMNA | |
| Hydrochloric Acid SCHEMBL19285070 | 0.63 | PSMB5 (0.32) | PTPN1PTPRCPTPRFCDC25BLMNA | |
| Hydrochloric Acid SCHEMBL4278507 | 0.63 | PSMB5 (0.32) | PTPN1PTPRCPTPRFCDC25BLMNA | |
| SCHEMBL29788366 | 0.63 | KDR (0.51) | PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8669330-B2 | Olefin triblock polymers via ring-opening metathesis polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-03-11 | — | — | US | claimed |
| US-20160289352-A1 | Functionalized Resins for High Performance Tires | EXXONMOBIL CHEMICAL PATENTS INC. | 2016-10-06 | — | — | US | disclosed |