Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10261443 | 0.89 | SMN1; SMN2 (0.51) | SMN1; SMN2HTTMAPTALDH1A1KMT2A | |
| SCHEMBL2474574 | 0.85 | CA1 (0.69) | SMN1; SMN2HTTMAPTALDH1A1KMT2A | |
| SCHEMBL2839421 | 0.85 | CA1 (0.69) | SMN1; SMN2HTTMAPTALDH1A1KMT2A | |
| SCHEMBL10261411 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2HTTMAPTALDH1A1KMT2A | |
| SCHEMBL3410189 | 0.79 | CA1 (0.61) | SMN1; SMN2HTTMAPTALDH1A1KMT2A | |
| SCHEMBL2469928 | 0.78 | CA1 (0.62) | SMN1; SMN2MAPTALDH1A1LMNACA1 | |
| SCHEMBL15512287 | 0.78 | NPC1 (0.42) | SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL2471917 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL3410024 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL13769050 | 0.74 | MAPT (0.66) | SMN1; SMN2HTTMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2706057-B1 | Bis(imidazolyl)compounds and radionuclide complexes | MOLECULAR INSIGHT PHARM INC (US) | 2016-04-20 | — | — | EP | disclosed |
| EP-2706057-A1 | Bis(imidazolyl)compounds and radionuclide complexes | Molecular Insight Pharmaceuticals, Inc. (US) | 2014-03-12 | — | — | EP | disclosed |