Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559006 | 0.91 | POLB (0.61) | MAPK1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL2562815 | 0.89 | ALDH1A1 (0.51) | MAPK1ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL2561941 | 0.89 | ALDH1A1 (0.51) | MAPK1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL2565658 | 0.89 | SMN1; SMN2 (0.52) | ALDH1A1MEN1KMT2ARAB9ANPSR1 | |
| SCHEMBL2566454 | 0.89 | ALDH1A1 (0.51) | MAPK1ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL2564148 | 0.89 | ALDH1A1 (0.51) | MAPK1ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL2565762 | 0.87 | ALDH1A1 (0.49) | MAPK1ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL2562976 | 0.87 | ALDH1A1 (0.49) | MAPK1ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL2567691 | 0.87 | ALDH1A1 (0.49) | MAPK1ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL2562510 | 0.87 | ALDH1A1 (0.49) | MAPK1ALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382194-B1 | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASE | RESVERLOGIX CORP (CA) | 2014-03-12 | — | — | EP | claimed |