Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 18/20 | 0.73 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | FPR1 | P21462 | 1/20 | 0.53 |
| ▸ | FPR3 | P25089 | 1/20 | 0.53 |
| ▸ | GPR183 | P32249 | 1/20 | 0.53 |
| ▸ | APLNR | P35414 | 1/20 | 0.53 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1551263 | 0.89 | FFAR1 (0.79) | FFAR1FFAR4CHRM2S1PR1FPR1 | |
| SCHEMBL12087485 | 0.85 | FFAR1 (1.00) | FFAR1FFAR4CHRM2S1PR1FPR1 | |
| SCHEMBL1550693 | 0.84 | FFAR1 (0.68) | FFAR1FFAR4CHRM2S1PR1FPR1 | |
| SCHEMBL1550423 | 0.83 | FFAR1 (0.69) | FFAR1FFAR4CHRM2S1PR1FPR1 | |
| SCHEMBL8455468 | 0.80 | FFAR1 (0.68) | FFAR1FFAR4CHRM2S1PR1FPR1 | |
| SCHEMBL19821418 | 0.79 | FFAR1 (0.64) | FFAR1FFAR4CHRM2S1PR1FPR1 | |
| SCHEMBL457584 | 0.78 | ACACB (0.60) | FFAR1CYP4F2CYP4A11 | |
| SCHEMBL12984047 | 0.77 | FFAR1 (0.71) | FFAR1FFAR4CHRM2S1PR1FPR1 | |
| SCHEMBL1551052 | 0.77 | FFAR1 (0.73) | FFAR1FFAR4CHRM2S1PR1FPR1 | |
| SCHEMBL8454687 | 0.77 | FFAR1 (0.63) | FFAR1FFAR4CHRM2S1PR1FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2313360-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISEASES | Syddansk Universitet (DK) | 2011-04-27 | — | — | EP | disclosed |
| WO-2010012650-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISEASES | SYDDANSK UNIVERSITET (DK) | 2010-02-04 | — | — | WO | disclosed |