SCHEMBL19821418

SCHEMBL19821418

CCOC(=O)CCCc1ccc(C#Cc2ccccc2C)cc1

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 17/20 0.64
FFAR4 Q5NUL3 2/20 0.64
CHRM2 P08172 1/20 0.64
S1PR1 P21453 1/20 0.64
FPR1 P21462 1/20 0.64
FPR3 P25089 1/20 0.64
GPR183 P32249 1/20 0.64
APLNR P35414 1/20 0.64
GPR65 Q8IYL9 1/20 0.64
ALOX5 P09917 1/20 0.51
CYP4Z1 Q86W10 1/20 0.47
CYP4F11 Q9HBI6 1/20 0.47
CYP4F12 Q9HCS2 1/20 0.47
CYP4F2 P78329 1/20 0.46
CYP4A11 Q02928 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19821417 0.84 FFAR1 (0.84) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL1551052 0.81 FFAR1 (0.73) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL1550693 0.80 FFAR1 (0.68) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL1551361 0.79 FFAR1 (0.73) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL1550423 0.79 FFAR1 (0.69) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL14924233 0.79 FFAR1 (0.79) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL29358680 0.79 FFAR1 (1.00) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL1551461 0.79 FFAR1 (1.00) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL1550405 0.78 FFAR1 (0.73) FFAR1FFAR4CHRM2S1PR1FPR1
SCHEMBL12064833 0.78 ALOX5 (0.72) ALOX5CYP4Z1CYP4F11CYP4F12CYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773077-B2 Compounds containing carbon-carbon linker as GPR120 agonists Piramal Enterprises Limited (IN) 2023-10-03 US disclosed
US-20180030031-A1 COMPOUNDS CONTAINING CARBON-CARBON LINKER AS GPR120 AGONISTS Piramal Enterprises Limited (IN) 2018-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11773077-B2 Compounds containing carbon-carbon linker as GPR120 agonists GPR180, GPR68, GPR88 FFAR1 20/4885FFAR4 42/4885CHRM2 150/4885
US-20180030031-A1 COMPOUNDS CONTAINING CARBON-CARBON LINKER AS GPR120 AGONISTS GPR180, GPR68, GPR88 FFAR1 20/4885FFAR4 42/4885CHRM2 150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.