SCHEMBL155148

SCHEMBL155148

[C]1=CCOC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL78418 0.67
SCHEMBL2241586 0.61
SCHEMBL2241592 0.61
SCHEMBL15510742 0.54
SCHEMBL5318324 0.54
SCHEMBL517175 0.51
SCHEMBL23964 0.51
SCHEMBL6517038 0.45
SCHEMBL18886880 0.45
SCHEMBL59324 0.45

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 905 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399209-A1 NEW QUINOLINE DERIVATIVES Elanco Animal Health GmbH (DE) 2024-07-17 EP claimed
CN-117957223-A Quinoline derivatives 礼蓝动物保健有限公司 2024-04-30 CN claimed
WO-2023247593-A1 PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS ACTELION PHARMACEUTICALS LTD (CH) 2023-12-28 WO claimed
EP-4284797-A1 PYRAZOLEAMIDE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2023-12-06 EP claimed
US-20230382911-A1 PYRAZOLEAMIDE DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 2023-11-30 US claimed
US-20230322695-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE BRISTOL-MYERS SQUIBB COMPANY 2023-10-12 US claimed
CN-116867782-A Pyrazole amide derivative 豪夫迈·罗氏有限公司 2023-10-10 CN claimed
WO-2023147531-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE BRISTOL-MYERS SQUIBB COMPANY (US) 2023-08-03 WO claimed
WO-2023036821-A1 NEW QUINOLINE DERIVATIVES BAYER ANIMAL HEALTH GMBH (DE) 2023-03-16 WO claimed
EP-4148052-A1 NEW QUINOLINE DERIVATIVES Bayer Animal Health GmbH (DE) 2023-03-15 EP claimed
WO-2014015934-A1 HYDROXYSTATIN DERIVATIVES FOR TREATMENT OF ARTHROSIS MERCK PATENT GMBH (DE) 2014-01-30 WO claimed
EP-2673287-A1 AMINO STATIN DERIVATIVES FOR THE TREATMENT OF ARTHROSIS Merck Patent GmbH (DE) 2013-12-18 EP claimed
EP-2670406-A1 COMBINATION THERAPY WITH INTERFERON AND ANDROGRAPHOLIDES FOR MULTIPLE SCLEROSIS Herbal Powers Corporation (US) 2013-12-11 EP claimed
WO-2013096423-A1 COMBINATION THERAPY WITH INTERFERON AND ANDROGRAPHOLIDES FOR MULTIPLE SCLEROSIS Herbal Powers Corporation (US) 2013-06-27 WO claimed
WO-2012107153-A1 AMINO STATIN DERIVATIVESFOR THE TREATMENT OF ARTHROSIS MERCK PATENT GMBH (DE) 2012-08-16 WO claimed
EP-1890543-A1 INCREASE OF STRESS TOLERANCE BY APPLICATION OF NEONICOTINOIDS ON PLANTS ENGINEERED TO BE STRESS TOLERANT Bayer CropScience Aktiengesellschaft (DE) 2008-02-27 EP claimed
CN-101076515-A Novel process for the manufacture of 3-pyrrolidin-2-yl-propionic acid derivatives HOFFMANN LA ROCHE (CH) 2007-11-21 CN claimed
WO-2006131222-A1 INCREASE OF STRESS TOLERANCE BY APPLICATION OF NEONICOTINOIDS ON PLANTS ENGINEERED TO BE STRESS TOLERANT BAYER CROPSCIENCE AG (DE) 2006-12-14 WO claimed
CN-1553897-A Dolastatin 10 derivatives - 2004-12-08 CN claimed
EP-0004435-A2 Ethers of 4-halomethylpyridines, fungicidal compositions and method for protecting plants from fungal disease THE DOW CHEMICAL COMPANY (US) 1979-10-03 EP claimed