⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12035161 | 1.00 | — | — | |
| SCHEMBL254735 | 1.00 | — | — | |
| SCHEMBL9695112 | 1.00 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL229160 | 1.00 | — | — | |
| SCHEMBL229159 | 1.00 | — | — | |
| SCHEMBL13748630 | 1.00 | — | — | |
| SCHEMBL155155 | 1.00 | — | — | |
| SCHEMBL9695108 | 1.00 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL158741 | 1.00 | — | — | |
| SCHEMBL1912136 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119569652-A | 2,2 '-Biquinoline-4, 4' -dicarboxylic acid aliphatic amino acid derivative, preparation and application thereof | 武汉大学人民医院（湖北省人民医院） | 2025-03-07 | — | — | CN | claimed |
| CN-119409587-A | Amino acid derivative of 2,2 '-binaphthyl-6, 6' -dicarboxylic acid, and preparation method and application thereof | 武汉大学人民医院（湖北省人民医院） | 2025-02-11 | — | — | CN | claimed |
| CN-118619923-A | Preparation method and application of tetrahydroisoquinoline PD-L1 inhibitor | 大连理工大学 | 2024-09-10 | — | — | CN | claimed |
| CN-114315957-B | Preparation method of polypeptide | 深圳瑞德林生物技术有限公司 | 2023-07-07 | — | — | CN | claimed |
| CN-114315957-A | Preparation method of polypeptide | 深圳瑞德林生物技术有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-111647050-B | Yi-lai-mycin F derivative and application thereof in preparation of mycobacterium tuberculosis resisting drugs | 中国科学院南海海洋研究所 | 2021-11-09 | — | — | CN | claimed |
| CN-111647050-A | Yi-lai-mycin F derivative and application thereof in preparation of mycobacterium tuberculosis resisting drugs | 中国科学院南海海洋研究所 | 2020-09-11 | — | — | CN | claimed |
| EP-3087192-B1 | METHOD OF PRODUCTION OF HUMAN INSULIN METHYL ESTER | BIOCON BIOLOGICS INDIA LTD (IN) | 2020-08-12 | — | — | EP | claimed |
| US-10611813-B2 | Method of production of human insulin methyl ester | BIOCON RESEARCH LIMITED (IN) | 2020-04-07 | — | — | US | claimed |
| CN-105849273-B | Process for the production of human insulin methyl ester | 拜康研究有限公司 | 2020-01-14 | — | — | CN | claimed |
| US-20170002052-A1 | Method of Production of Human Insulin Methyl Ester | BIOCON BIOLOGICS INDIA LIMITED (IN) | 2017-01-05 | — | — | US | claimed |
| EP-3087192-A1 | METHOD OF PRODUCTION OF HUMAN INSULIN METHYL ESTER | Biocon Research Limited (IN) | 2016-11-02 | — | — | EP | claimed |
| WO-2015097643-A1 | METHOD OF PRODUCTION OF HUMAN INSULIN METHYL ESTER | BIOCON RESEARCH LIMITED (IN) | 2015-07-02 | — | — | WO | claimed |
| EP-0085083-B1 | PROCESS FOR THE ENZYMATIC PREPARATION OF HUMAN INSULIN | NORDISK INSULINLABORATORIUM (DK) | 1985-01-23 | — | — | EP | claimed |
| WO-1984003107-A1 | A PROCESS FOR THE PREPARATION OF HUMAN INSULIN | NORDISK INSULINLAB (DK) | 1984-08-16 | — | — | WO | claimed |
| EP-0085083-A1 | Process for the enzymatic preparation of human insulin. | NORDISK INSULINLAB (DK) | 1983-08-10 | — | — | EP | claimed |
| WO-1983000504-A1 | ENZYMATIC PREPARATION OF HUMAN INSULIN | ANDRESEN, FINN, HEDE | 1983-02-17 | — | — | WO | claimed |
| CN-119409587-B | Amino acid derivative of 2,2 '-binaphthyl-6, 6' -dicarboxylic acid, and preparation method and application thereof | Renmin Hospital Of Wuhan University (hubei General Hospital) (CN) | 2026-05-26 | — | — | CN | disclosed |
| EP-0045187-A1 | A process for enzymatic replacement of the B-30 amino acid in insulins | DE FORENEDE BRYGGERIER A/S (DK) | 1982-02-03 | — | — | EP | disclosed |
| US-4273704-A | N-Adamantane-substituted tetrapeptide amides | G. D. SEARLE & CO. (US) | 1981-06-16 | — | — | US | disclosed |