SCHEMBL254735

SCHEMBL254735

COC(=O)[C@@H](N)[C@H](C)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL155154 1.00
SCHEMBL12035161 1.00
SCHEMBL9695112 1.00 SMN1; SMN2 (0.42)
SCHEMBL229160 1.00
SCHEMBL229159 1.00
SCHEMBL13748630 1.00
SCHEMBL155155 1.00
SCHEMBL9695108 1.00 SMN1; SMN2 (0.42)
SCHEMBL158741 1.00
SCHEMBL1912136 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001889-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS INC (US) 2026-01-01 US disclosed
EP-4522622-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING Skyhawk Therapeutics, Inc. (US) 2025-03-19 EP disclosed
WO-2023220439-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. (US) 2023-11-16 WO disclosed
WO-2023220439-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. (US) 2023-11-16 WO disclosed
US-20230159519-A1 NOVEL COMPOUNDS AND THEIR USE DEBIOPHARM INTERNATIONAL S.A. (CH) 2023-05-25 US disclosed
CN-108368032-B Phenolic acid derivative compound and application thereof 大峰LS株式会社 2021-06-08 CN disclosed
US-10696623-B2 Phenolic acid derivative compound and use thereof DAEBONG LS, LTD (KR) 2020-06-30 US disclosed
US-20180362448-A1 NOVEL PHENOLIC ACID DERIVATIVE COMPOUND AND USE THEREOF DAEBONG LS, LTD (KR) 2018-12-20 US disclosed
CN-108368032-A Novel phenolic acid class derivative compound and application thereof 大峰LS株式会社 2018-08-03 CN disclosed
US-9839641-B2 Compounds and methods for treating bacterial infections ENTASIS THERAPEUTICS LIMITED (GB) 2017-12-12 US disclosed
US-20090163496-A1 ANTIBACTERIAL AGENTS UNIVERSITY OF WASHINGTON (US) 2009-06-25 US disclosed
WO-2008154642-A2 ANTIBACTERIAL AGENTS ACHAOGEN, INC. (US) 2008-12-18 WO disclosed
US-7358359-B2 Antibacterial agents UNIVERSITY OF WASHINGTON (US) 2008-04-15 US disclosed
WO-2008028937-A1 N-BIARYL (HETERO) ARYLSULPHONAMIDE DERIVATIVES USEFUL IN THE TREATMENT OF DISEASES MEDIATED BY LYMPHOCYTES INTERACTIONS NOVARTIS AG (CH) 2008-03-13 WO disclosed
US-20070244197-A1 Antibacterial agents UNIVERSITY OF WASHINGTON (US) 2007-10-18 US disclosed
US-20070244197-A1 Antibacterial agents UNIVERSITY OF WASHINGTON (US) 2007-10-18 US disclosed
US-7183417-B2 Simple stereocontrolled synthesis of salinosporamide A PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2007-02-27 US disclosed
EP-1745048-A2 SIMPLE STEREOCONTROLLED SYNTHESIS OF SALINOSPORAMIDE A The President and Fellows of Harvard College (US) 2007-01-24 EP disclosed
WO-2005113558-A2 SIMPLE STEREOCONTROLLED SYNTHESIS OF SALINOSPORAMIDE A PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2005-12-01 WO disclosed
US-20050228186-A1 Simple stereocontrolled synthesis of salinosporamide A PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2005-10-13 US disclosed