Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15664759 | 0.90 | KIT (1.00) | KIT | |
| SCHEMBL15515827 | 0.87 | KIT (0.79) | KIT | |
| SCHEMBL15515696 | 0.85 | KIT (0.79) | KIT | |
| SCHEMBL15515316 | 0.85 | KIT (0.80) | KIT | |
| SCHEMBL15515978 | 0.81 | KIT (0.62) | KIT | |
| SCHEMBL15664573 | 0.81 | KIT (1.00) | KIT | |
| SCHEMBL15515412 | 0.79 | KIT (0.79) | KIT | |
| SCHEMBL15516953 | 0.78 | KIT (0.75) | KIT | |
| SCHEMBL15663671 | 0.78 | KIT (1.00) | KIT | |
| SCHEMBL15664565 | 0.78 | KIT (1.00) | KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2892534-A2 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | Plexxikon, Inc. (US) | 2015-07-15 | — | — | EP | disclosed |
| WO-2014039714-A2 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC. (US) | 2014-03-13 | — | — | WO | disclosed |