Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SCN4A | P35499 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496496 | 0.98 | LMNA (0.61) | LMNASCN4AMEN1KMT2AOPRM1 | |
| SCHEMBL30987975 | 0.98 | LMNA (0.61) | LMNASCN4AMEN1KMT2AOPRM1 | |
| SCHEMBL1496743 | 0.90 | LMNA (0.53) | LMNASCN4AMEN1KMT2AOPRM1 | |
| SCHEMBL22289126 | 0.86 | HIF1A (0.57) | LMNASCN4AMEN1KMT2AOPRM1 | |
| SCHEMBL23151835 | 0.85 | LMNA (0.52) | LMNASCN4AMEN1KMT2AOPRM1 | |
| SCHEMBL1496572 | 0.85 | LMNA (0.52) | LMNASCN4AMEN1KMT2ALTA4H | |
| SCHEMBL1496739 | 0.85 | MEN1 (0.53) | LMNASCN4AMEN1KMT2ALTA4H | |
| SCHEMBL9534764 | 0.85 | LMNA (0.47) | LMNASCN4AMEN1KMT2AOPRM1 | |
| SCHEMBL1496649 | 0.85 | SCN4A (0.65) | LMNASCN4AMEN1KMT2ALTA4H | |
| SCHEMBL1496702 | 0.85 | KMT2A (0.58) | LMNAKMT2ALTA4HL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2892867-A1 | CLEAVAGE OF A BETA-O-4 BOND IN ETHERS | Kat2Biz AB (SE) | 2015-07-15 | — | — | EP | disclosed |
| WO-2014039002-A1 | CLEAVAGE OF A B-O-4 BOND IN ETHERS | KAT2BIZAB (SE) | 2014-03-13 | — | — | WO | disclosed |