SCHEMBL1551622

SCHEMBL1551622

CC(C)CN(CCCCO)CC(C)C

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.36
MAPK1 P28482 1/20 0.36
CA12 O43570 3/20 0.34
CA1 P00915 3/20 0.34
CA2 P00918 3/20 0.34
CA9 Q16790 3/20 0.34
ALDH1A1 P00352 2/20 0.33
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 2/20 0.32
TSHR P16473 2/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL556846 0.92 CYP1A2 (0.37) CYP1A2MAPK1CA12CA1CA2
SCHEMBL4290820 0.91 MAPT (0.36) CYP1A2MAPK1CA12CA1CA2
SCHEMBL21359044 0.87 CYP1A2 (0.37) CYP1A2MAPK1CA12CA1CA2
SCHEMBL15015862 0.87 CYP1A2 (0.43) CYP1A2MAPK1CA12CA1CA2
SCHEMBL10706034 0.84 ALDH1A1 (0.42) CYP1A2MAPK1CA12CA1CA2
SCHEMBL25489387 0.83 TDP1 (0.35) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10
SCHEMBL3427669 0.83 MAPT (0.38) CYP1A2MAPK1CA12CA1CA2
SCHEMBL9641431 0.83 MAPT (0.38) CYP1A2MAPK1CA12CA1CA2
SCHEMBL557796 0.81 MAPT (0.45) CYP1A2MAPK1CA12CA1CA2
SCHEMBL25956497 0.81 CYP1A2 (0.33) CYP1A2MAPK1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8778842-B2 Sample lysis and coating of reaction surface QIAGEN GMBH (DE) 2014-07-15 US claimed
CN-101748117-B Sample dissociation and coating of reaction surface QIAGEN GMBH 2014-03-26 CN claimed
EP-1856168-B1 SAMPLE LYSIS AND COATING OF REACTION SURFACE QIAGEN GMBH (DE) 2011-04-27 EP claimed
US-20080299557-A1 Sample Lysis and Coating of Reaction Surface QIAGEN GMBH (DE) 2008-12-04 US claimed
JP-60132934-A None JP disclosed
CN-107540565-A The preparation of N, N (two) alkyl amino alkyl (methyl) acrylamide or corresponding ester and its quaternary ammonium salt 赢创罗姆有限公司 2018-01-05 CN disclosed
US-8778842-B2 Sample lysis and coating of reaction surface QIAGEN GMBH (DE) 2014-07-15 US disclosed
CN-101748117-B Sample dissociation and coating of reaction surface QIAGEN GMBH 2014-03-26 CN disclosed
EP-1856168-B1 SAMPLE LYSIS AND COATING OF REACTION SURFACE QIAGEN GMBH (DE) 2011-04-27 EP disclosed
CN-101748117-A Sample dissociation and coating of reaction surface QIAGEN GMBH 2010-06-23 CN disclosed
US-7592489-B2 fluoroalkyl phosphate solution containing cationic copolymer of fluoroalkyl(meth)acrylate or perfluoroalkylether(meth)acrylate provides water repellency to surface without etching E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-09-22 US disclosed
US-20080299557-A1 Sample Lysis and Coating of Reaction Surface QIAGEN GMBH (DE) 2008-12-04 US disclosed
US-4366299-A Copolymers containing fluorine and their use for the water-repellent and oil-repellent treatment of various substrates P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1982-12-28 US disclosed
EP-0009154-B1 COMPLEXES OF 9-HYDROXYALKYL-PURINES, PROCESSES FOR PREPARING THEM AND THERAPEUTICAL COMPOSITIONS CONTAINING THE COMPLEXES AS ACTIVE INGREDIENTS Newport Pharmaceuticals International, Inc. (US) 1982-12-08 EP disclosed
EP-0009155-B1 9-HYDROXYALKYL-PURINES, PROCESSES FOR PREPARING THEM AND THERAPEUTICAL COMPOSITION CONTAINING THE 9-HYDROXYALKYL-PURINES AS ACTIVE INGREDIENTS Newport Pharmaceuticals International, Inc. (US) 1982-11-17 EP disclosed
US-4221910-A IMMUNOPOTENTIATORS, VIRICIDES, ANTILEUKEMIA AGENTS NEWPORT PHARMACEUTICALS INTERNATIONAL, INC. (US) 1980-09-09 US disclosed
US-4221909-A P-Acetamidobenzoic acid salts of 9-(hydroxyalkyl) purines SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1980-09-09 US disclosed
US-4221794-A Method of imparting immunomodulating and antiviral activity NEWPORT PHARMACEUTICALS INTERNATIONAL, INC. (US) 1980-09-09 US disclosed
EP-0009155-A1 9-Hydroxyalkyl-purines, processes for preparing them and therapeutical composition containing the 9-hydroxyalkyl-purines as active ingredients Newport Pharmaceuticals International, Inc. (US) 1980-04-02 EP disclosed
EP-0009154-A1 Complexes of 9-hydroxyalkyl-purines, processes for preparing them and therapeutical compositions containing the complexes as active ingredients Newport Pharmaceuticals International, Inc. (US) 1980-04-02 EP disclosed