Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.46 |
| ▸ | GSK3A | P49840 | 5/20 | 0.45 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | SYK | P43405 | 2/20 | 0.45 |
| ▸ | GRN | P28799 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 5/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15516834 | 0.85 | ALDH1A1 (0.45) | ALDH1A1GAAGSK3ASRCSYK | |
| SCHEMBL15516500 | 0.83 | KLKB1 (0.46) | ALDH1A1GAAKLKB1GSK3ASRC | |
| SCHEMBL15517438 | 0.82 | GRN (0.64) | ALDH1A1KLKB1GSK3ASRCSYK | |
| SCHEMBL4498910 | 0.79 | ALDH1A1 (1.00) | ALDH1A1GAAGRNSORT1MAPK14 | |
| SCHEMBL2927650 | 0.77 | ALDH1A1 (0.74) | ALDH1A1GAAKLKB1GRNSORT1 | |
| SCHEMBL2926051 | 0.74 | ALDH1A1 (0.68) | ALDH1A1GAAKLKB1GRNSORT1 | |
| SCHEMBL15518413 | 0.71 | ALDH1A1 (0.50) | ALDH1A1GAAKMT2APOLBTDP1 | |
| SCHEMBL15516625 | 0.71 | GRN (0.62) | ALDH1A1KLKB1GRNSORT1CARM1 | |
| SCHEMBL4422536 | 0.70 | ALDH1A1 (0.75) | ALDH1A1GAAGRNSORT1MAPK14 | |
| SCHEMBL15517487 | 0.70 | ALDH1A1 (0.48) | ALDH1A1GAAKMT2APOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796742-B2 | Kinase inhibitors | RESPIVERT LIMITED (GB) | 2017-10-24 | — | — | US | disclosed |
| EP-2890460-B1 | KINASE INHIBITORS | RESPIVERT LTD (GB) | 2017-02-22 | — | — | EP | disclosed |
| US-20160340375-A1 | KINASE INHIBITORS | OXULAR ACQUISITIONS LIMITED (GB) | 2016-11-24 | — | — | US | disclosed |
| US-20150210722-A1 | KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2015-07-30 | — | — | US | disclosed |
| EP-2890460-A1 | KINASE INHIBITORS | Respivert Limited (GB) | 2015-07-08 | — | — | EP | disclosed |
| WO-2014033446-A1 | KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2014-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210722-A1 | KINASE INHIBITORS | SYK, SRC, LYN | ALDH1A1 2702/4885GAA 1725/4885KLKB1 2074/4885 |
| US-20160340375-A1 | KINASE INHIBITORS | SYK, LYN, BTK | ALDH1A1 2639/4885GAA 1883/4885KLKB1 2137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.