Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | BDKRB1 | P46663 | 14/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL325428 | 0.92 | BDKRB1 (0.39) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3462517 | 0.91 | BDKRB1 (0.40) | P2RX7BDKRB1 | |
| SCHEMBL12745124 | 0.90 | CA12 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15516994 | 0.90 | BDKRB1 (0.42) | P2RX7BDKRB1HTR1AHTR2AKCNH2 | |
| SCHEMBL15516270 | 0.90 | CYP11B2 (0.40) | BDKRB1 | |
| SCHEMBL12745005 | 0.86 | BDKRB1 (0.37) | BDKRB1 | |
| SCHEMBL1465860 | 0.86 | TRPV1 (0.41) | BDKRB1 | |
| SCHEMBL12745306 | 0.86 | BDKRB1 (0.46) | BDKRB1 | |
| SCHEMBL327626 | 0.82 | CA12 (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL807572 | 0.82 | CYP11B2 (0.41) | BDKRB1HTR1AHTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150208658-A1 | METHODS OF SOIL PEST CONTROL | SYNGENTA PARTICIPATIONS AG (CH) | 2015-07-30 | — | — | US | disclosed |
| US-20150189884-A1 | METHODS OF CONTROLLING INSECTS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-07-09 | — | — | US | disclosed |
| EP-2887802-A2 | METHODS OF SOIL PEST CONTROL | Syngenta Participations AG (CH) | 2015-07-01 | — | — | EP | disclosed |
| US-20150152070-A1 | METHODS OF PEST CONTROL IN SOYBEAN | SYNGENTA PARICIPATIONS AG (CH) | 2015-06-04 | — | — | US | disclosed |
| WO-2014029706-A2 | METHODS OF CONTROLLING INSECTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | WO | disclosed |
| WO-2014029710-A2 | METHODS OF SOIL PEST CONTROL | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | WO | disclosed |
| WO-2014029708-A1 | METHODS OF CONTROLLING INSECTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | WO | disclosed |
| WO-2014029707-A1 | METHODS OF CONTROLLING INSECTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | WO | disclosed |
| WO-2014019957-A2 | METHODS OF PEST CONTROL IN SOYBEAN | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150189884-A1 | METHODS OF CONTROLLING INSECTS | CBR3, C5, CNPY3 | CA12 1769/4885CA1 1402/4885CA2 597/4885 |
| US-20150152070-A1 | METHODS OF PEST CONTROL IN SOYBEAN | C1S, ATL3, CCNB3 | CA12 2374/4885CA1 1821/4885CA2 1191/4885 |
| US-20150208658-A1 | METHODS OF SOIL PEST CONTROL | C1S, CBR3, CNPY3 | CA12 1643/4885CA1 499/4885CA2 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.