SCHEMBL15517359

SCHEMBL15517359

FC(F)(F)c1cc(Cl)cc(C2[CH]CCO2)c1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.32
NOTUM Q6P988 1/20 0.32
RAPGEF4 Q8WZA2 1/20 0.31
ACLY P53396 1/20 0.31
TACR1 P25103 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15561970 0.89 TACR1 (0.37) HTR1ANOTUMTACR1
SCHEMBL15516981 0.81 HTR1A (0.35) HTR1ANOTUMTACR1
SCHEMBL15517019 0.76
SCHEMBL7784381 0.75 HTR1A (0.36) HTR1ANOTUMRAPGEF4ACLYTACR1
SCHEMBL15516510 0.72 NPSR1 (0.30)
SCHEMBL15516784 0.71
SCHEMBL15516781 0.71 SLC6A2 (0.40)
SCHEMBL1659020 0.71 NOTUM (0.46) NOTUMRAPGEF4ACLY
SCHEMBL15517601 0.69
SCHEMBL15516386 0.68 NOTUM (0.41) NOTUMRAPGEF4ACLY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2887802-A2 METHODS OF SOIL PEST CONTROL Syngenta Participations AG (CH) 2015-07-01 EP disclosed
WO-2014029708-A1 METHODS OF CONTROLLING INSECTS SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014029706-A2 METHODS OF CONTROLLING INSECTS SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014029707-A1 METHODS OF CONTROLLING INSECTS SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014029710-A2 METHODS OF SOIL PEST CONTROL SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014019609-A1 METHODS OF PEST CONTROL IN SOYBEAN SYNGENTA PARTICIPATIONS AG (CH) 2014-02-06 WO disclosed