Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 3/20 | 0.47 |
| ▸ | MAN1B1 | Q9UKM7 | 6/20 | 0.38 |
| ▸ | MAN2A1 | Q16706 | 5/20 | 0.38 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.38 |
| ▸ | HEXA | P06865 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15574485 | 0.90 | OGA (0.53) | OGAMAN1B1MAN2A1MAN2B1HEXA | |
| SCHEMBL15517239 | 0.83 | MAN1B1 (0.38) | OGAMAN1B1MAN2A1MAN2B1GBA1 | |
| SCHEMBL15574089 | 0.80 | OGA (0.40) | OGAMAN1B1MAN2A1MAN2B1GBA1 | |
| SCHEMBL15574953 | 0.77 | GLA (0.49) | MAN1B1MAN2A1MAN2B1HEXAGBA1 | |
| SCHEMBL15516920 | 0.74 | MAN1B1 (0.36) | OGAMAN1B1MAN2A1MAN2B1GBA1 | |
| SCHEMBL15517614 | 0.74 | MAN1B1 (0.36) | OGAMAN1B1MAN2A1MAN2B1GBA1 | |
| SCHEMBL15517022 | 0.74 | MAN1B1 (0.36) | OGAMAN1B1MAN2A1MAN2B1GBA1 | |
| SCHEMBL15517130 | 0.74 | MAN1B1 (0.36) | OGAMAN1B1MAN2A1MAN2B1GBA1 | |
| SCHEMBL15517963 | 0.72 | BCHE (0.41) | OGAMAN1B1MAN2A1 | |
| SCHEMBL15517028 | 0.72 | MAN1B1 (0.40) | OGAMAN1B1MAN2A1MAN2B1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2890678-A1 | GLYCOSIDASE INHIBITORS AND USES THEREOF | Alectos Therapeutics Inc. (CA) | 2015-07-08 | — | — | EP | claimed |
| WO-2014032187-A1 | GLYCOSIDASE INHIBITORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2014-03-06 | — | — | WO | claimed |
| EP-2890678-A1 | GLYCOSIDASE INHIBITORS AND USES THEREOF | Alectos Therapeutics Inc. (CA) | 2015-07-08 | — | — | EP | disclosed |
| WO-2014032187-A1 | GLYCOSIDASE INHIBITORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2014-03-06 | — | — | WO | disclosed |