⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10920598 | 0.97 | CES2 (0.56) | — | |
| SCHEMBL6467971 | 0.97 | CES2 (0.56) | — | |
| SCHEMBL9114320 | 0.97 | CES2 (0.56) | — | |
| SCHEMBL1898398 | 0.97 | CES2 (0.56) | — | |
| SCHEMBL15809443 | 0.97 | CES2 (0.56) | — | |
| SCHEMBL9459406 | 0.97 | CES2 (0.56) | — | |
| SCHEMBL17078442 | 0.97 | CES2 (0.56) | — | |
| SCHEMBL3076861 | 0.92 | — | — | |
| SCHEMBL7853657 | 0.87 | PPARG (0.66) | — | |
| SCHEMBL126793 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | claimed |
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |
| WO-2002049433-A2 | REPELLENT COSMETIC COMPOSITION ACTIVE AGAINST SCHISTOSOME FURCOCERCARIA | LABORATOIRES ASEPTA S.A.M. (MC) | 2002-06-27 | — | — | WO | claimed |
| CN-110997662-B | Benzimidazole derivatives as adenosine receptor antagonists | 默克专利股份公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-110944994-B | Quinoxaline derivatives as adenosine receptor antagonists | 默克专利股份公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-110997681-B | Thiazolopyridine derivatives as adenosine receptor antagonists | 默克专利股份公司 | 2022-11-15 | — | — | CN | disclosed |
| EP-3810119-A2 | <SUP2/>? <SUB2/>?+? ?COMPOSITIONS AND METHODS USING A NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD) PRECURSOR AND AT LEAST ONE KETONE OR KETONE PRECURSOR | Société des Produits Nestlé S.A. (CH) | 2021-04-28 | — | — | EP | disclosed |
| CN-108752241-B | Acylguanidines for the treatment of arthrosis | 默克专利股份公司 | 2021-03-12 | — | — | CN | disclosed |
| CN-105263900-B | Hydroxy ethylene derivatives for the treatment of arthrosis | 默克专利股份公司 | 2020-09-22 | — | — | CN | disclosed |
| CN-105102424-B | Acylguanidines for the treatment of arthrosis | 默克专利股份公司 | 2020-09-11 | — | — | CN | disclosed |
| CN-110997662-A | Benzimidazole derivatives as adenosine receptor antagonists | 默克专利股份公司 | 2020-04-10 | — | — | CN | disclosed |
| EP-1419137-A2 | METHOD FOR PRODUCING ACYL AMINO ACIDS | Cognis Deutschland GmbH & Co. KG (DE) | 2004-05-19 | — | — | EP | disclosed |
| EP-1299074-A2 | DEODORIZING PREPARATIONS CONTAINING DIALKYL CARBONATES AND PROPELLANTS AND THEIR USE AS AEROSOLS | Cognis Deutschland GmbH & Co. KG (DE) | 2003-04-09 | — | — | EP | disclosed |
| WO-2002049433-A3 | REPELLENT COSMETIC COMPOSITION ACTIVE AGAINST SCHISTOSOME FURCOCERCARIA | ASEPTA S A M LAB (MC) | 2003-01-03 | — | — | WO | disclosed |
| WO-2002057217-A2 | METHOD FOR PRODUCING ACYL AMINO ACIDS | COGNIS DEUTSCHLAND GMBH & CO. KG (DE) | 2002-07-25 | — | — | WO | disclosed |
| WO-2002049433-A2 | REPELLENT COSMETIC COMPOSITION ACTIVE AGAINST SCHISTOSOME FURCOCERCARIA | LABORATOIRES ASEPTA S.A.M. (MC) | 2002-06-27 | — | — | WO | disclosed |
| WO-2002049433-A2 | REPELLENT COSMETIC COMPOSITION ACTIVE AGAINST SCHISTOSOME FURCOCERCARIA | LABORATOIRES ASEPTA S.A.M. (MC) | 2002-06-27 | — | — | WO | disclosed |
| WO-2002003927-A2 | DEODORIZING PREPARATIONS CONTAINING DIALKYL CARBONATES AND PROPELLANTS AND THEIR USE AS AEROSOLS | COGNIS DEUTSCHLAND GMBH & CO. KG (DE) | 2002-01-17 | — | — | WO | disclosed |
| CN-1101044-A | 2-(3-oxoalk(en)yl)-3-isothiazolones and derivatives as antimicrobial agents | ROHM & HAAS (US) | 1995-04-05 | — | — | CN | disclosed |
| US-5387603-A | Treating dysuria (painful urination) with less hypotension; FDA Orange book listed patent for silodosin | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |