SCHEMBL1551890

SCHEMBL1551890

CC(C)(C)c1ccc(OP(=O)(Cl)Cl)c(C(C)(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
CYP2C19 P33261 1/20 0.39
ALDH1A1 P00352 3/20 0.36
NPC1 O15118 1/20 0.36
PLA2G1B P04054 1/20 0.36
NFKB1 P19838 1/20 0.36
CASP3 P42574 1/20 0.36
RAB9A P51151 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ATG4B Q9Y4P1 1/20 0.36
MAPK1 P28482 2/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1931568 0.90 APEX1 (0.40) APEX1CA1CA2CA9CYP2C19
SCHEMBL9346703 0.87 APEX1 (0.41) APEX1CA1CA2CA9CYP2C19
SCHEMBL82774 0.86 CA1 (0.42) APEX1CA1CA2CA9CYP2C19
SCHEMBL29355190 0.86 CA1 (0.42) APEX1CA1CA2CA9CYP2C19
SCHEMBL1931570 0.83 APEX1 (0.39) APEX1CA1CA2CA9CYP2C19
SCHEMBL1551891 0.83 APEX1 (0.39) APEX1CA1CA2CA9CYP2C19
SCHEMBL11805176 0.83 APEX1 (0.40) APEX1CA1CA2CA9CYP2C19
SCHEMBL29373261 0.83 APEX1 (0.40) APEX1CA1CA2CA9CYP2C19
SCHEMBL8336189 0.83 CA1 (0.40) APEX1CA1CA2CA9CYP2C19
SCHEMBL30744579 0.83 INPPL1 (0.46) APEX1CA1CA2CA9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8039535-B2 Flame retardant and impact modifier, method for preparing the same, and thermoplastic resin composition including the same CHEIL INDUSTRIES INC. (KR) 2011-10-18 US claimed
EP-2143754-B1 Flame retardent and impact modifier, method for preparing thereof, and thermoplastic resin composition containing the same CHEIL IND INC (KR) 2011-04-27 EP claimed
EP-2143754-A1 Flame retardent and impact modifier, method for preparing thereof, and thermoplastic resin composition containing the same Cheil Industries Inc. (KR) 2010-01-13 EP claimed
US-20100004364-A1 Flame Retardant and Impact Modifier, Method for Preparing the Same, and Thermoplastic Resin Composition Including the Same CHEIL INDUSTRIES INC. (KR) 2010-01-07 US claimed
CN-101619142-B Flame retardant and impact modifier, method for preparing the same, and thermoplastic resin composition including the same CHEIL IND INC 2012-06-06 CN disclosed
US-8039535-B2 Flame retardant and impact modifier, method for preparing the same, and thermoplastic resin composition including the same CHEIL INDUSTRIES INC. (KR) 2011-10-18 US disclosed
US-8039535-B2 Flame retardant and impact modifier, method for preparing the same, and thermoplastic resin composition including the same CHEIL INDUSTRIES INC. (KR) 2011-10-18 US disclosed
US-7956111-B2 Non-halogen flameproof polycarbonate resin composition CHEIL INDUSTRIES, INC. (KR) 2011-06-07 US disclosed
EP-2143754-B1 Flame retardent and impact modifier, method for preparing thereof, and thermoplastic resin composition containing the same CHEIL IND INC (KR) 2011-04-27 EP disclosed
US-20100152345-A1 Non-Halogen Flameproof Polycarbonate Resin Composition CHEIL INDUSTRIES INC. (KR) 2010-06-17 US disclosed
JP-2010013649-A FLAME-RETARDING AND IMPACT-MODIFYING AGENT, METHOD FOR PRODUCING THE SAME AND THERMOPLASTIC RESIN COMPOSITION CONTAINING THE SAME CHEIL INDUSTRIES INC 2010-01-21 JP disclosed
EP-2143754-A1 Flame retardent and impact modifier, method for preparing thereof, and thermoplastic resin composition containing the same Cheil Industries Inc. (KR) 2010-01-13 EP disclosed
US-20100004364-A1 Flame Retardant and Impact Modifier, Method for Preparing the Same, and Thermoplastic Resin Composition Including the Same CHEIL INDUSTRIES INC. (KR) 2010-01-07 US disclosed
US-20100004364-A1 Flame Retardant and Impact Modifier, Method for Preparing the Same, and Thermoplastic Resin Composition Including the Same CHEIL INDUSTRIES INC. (KR) 2010-01-07 US disclosed
CN-101619142-A Flame retardant and impact modifier, method for preparing the same, and thermoplastic resin composition including the same CHEIL IND INC 2010-01-06 CN disclosed
US-4298520-A PHOSPHITES OR PHOSPHATES ARGUS CHEMICAL CORP. (US) 1981-11-03 US disclosed
US-4293472-A O-ALKYLHYDROXYBENZYLPROPANE-1,3-DIOL ESTERS CONTAINING SULFIDE GROUPS ADEKA ARGUS CHEMICAL CO., LTD. 1981-10-06 US disclosed
US-4171298-A SUBSTITUTED ORTHO-ALKYLHYDROXYBENZYLPROPANE-1,3-DIOL ESTERS ARGUS CHEMICAL CORPORATION (US) 1979-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100004364-A1 Flame Retardant and Impact Modifier, Method for Preparing the Same, and Thermoplastic Resin Composition Including the Same TAF1, TAF5, AFF1 APEX1 2295/4885CA1 2577/4885CA2 3615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.