SCHEMBL1551891

SCHEMBL1551891

CC(C)(C)c1ccc(OP(=O)(OCl)OCl)c(C(C)(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
CYP2C19 P33261 1/20 0.37
MAPK1 P28482 2/20 0.34
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
TRPV1 Q8NER1 1/20 0.34
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33
KDM4E B2RXH2 2/20 0.33
ATM Q13315 1/20 0.32
ALDH1A1 P00352 3/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1931570 0.97 APEX1 (0.39) APEX1CA1CA2CA9CYP2C19
SCHEMBL29355190 0.90 CA1 (0.42) APEX1CA1CA2CA9CYP2C19
SCHEMBL82774 0.90 CA1 (0.42) APEX1CA1CA2CA9CYP2C19
Phosphoric Acid SCHEMBL31374284 0.85 APEX1 (0.40) APEX1CA1CA2CA9CYP2C19
SCHEMBL28169938 0.85 CA1 (0.39) APEX1CA1CA2CA9CYP2C19
SCHEMBL10446431 0.84 APEX1 (0.40) APEX1CA1CA2CA9CYP2C19
SCHEMBL15288906 0.84 APEX1 (0.39) APEX1CA1CA2CA9CYP2C19
SCHEMBL16859696 0.84 CYP3A4 (0.43) APEX1CA1CA2CA9CYP2C19
SCHEMBL1426519 0.84 CA1 (0.38) APEX1CA1CA2CA9CYP2C19
SCHEMBL1551890 0.83 APEX1 (0.40) APEX1CA1CA2CA9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8039535-B2 Flame retardant and impact modifier, method for preparing the same, and thermoplastic resin composition including the same CHEIL INDUSTRIES INC. (KR) 2011-10-18 US claimed
EP-2143754-B1 Flame retardent and impact modifier, method for preparing thereof, and thermoplastic resin composition containing the same CHEIL IND INC (KR) 2011-04-27 EP claimed
EP-2143754-A1 Flame retardent and impact modifier, method for preparing thereof, and thermoplastic resin composition containing the same Cheil Industries Inc. (KR) 2010-01-13 EP claimed
US-20100004364-A1 Flame Retardant and Impact Modifier, Method for Preparing the Same, and Thermoplastic Resin Composition Including the Same CHEIL INDUSTRIES INC. (KR) 2010-01-07 US claimed
CN-101619142-B Flame retardant and impact modifier, method for preparing the same, and thermoplastic resin composition including the same CHEIL IND INC 2012-06-06 CN disclosed
US-8039535-B2 Flame retardant and impact modifier, method for preparing the same, and thermoplastic resin composition including the same CHEIL INDUSTRIES INC. (KR) 2011-10-18 US disclosed
US-7956111-B2 Non-halogen flameproof polycarbonate resin composition CHEIL INDUSTRIES, INC. (KR) 2011-06-07 US disclosed
EP-2143754-B1 Flame retardent and impact modifier, method for preparing thereof, and thermoplastic resin composition containing the same CHEIL IND INC (KR) 2011-04-27 EP disclosed
US-20100152345-A1 Non-Halogen Flameproof Polycarbonate Resin Composition CHEIL INDUSTRIES INC. (KR) 2010-06-17 US disclosed
JP-2010013649-A FLAME-RETARDING AND IMPACT-MODIFYING AGENT, METHOD FOR PRODUCING THE SAME AND THERMOPLASTIC RESIN COMPOSITION CONTAINING THE SAME CHEIL INDUSTRIES INC 2010-01-21 JP disclosed
EP-2143754-A1 Flame retardent and impact modifier, method for preparing thereof, and thermoplastic resin composition containing the same Cheil Industries Inc. (KR) 2010-01-13 EP disclosed
US-20100004364-A1 Flame Retardant and Impact Modifier, Method for Preparing the Same, and Thermoplastic Resin Composition Including the Same CHEIL INDUSTRIES INC. (KR) 2010-01-07 US disclosed
CN-101619142-A Flame retardant and impact modifier, method for preparing the same, and thermoplastic resin composition including the same CHEIL IND INC 2010-01-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100004364-A1 Flame Retardant and Impact Modifier, Method for Preparing the Same, and Thermoplastic Resin Composition Including the Same TAF1, TAF5, AFF1 APEX1 2295/4885CA1 2577/4885CA2 3615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.