Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CCR9 | P51686 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14054316 | 0.87 | NOD2 (0.48) | RORCMAPTPPARGPPARAPPARD | |
| SCHEMBL14124687 | 0.84 | PPARG (0.41) | RORCMAPTTP53PPARGALDH1A1 | |
| SCHEMBL14124693 | 0.82 | MRGPRX4 (0.41) | RORCPPARGALDH1A1PPARAPPARD | |
| SCHEMBL14057067 | 0.82 | PPARG (0.39) | RORCMAPTTP53PPARGALDH1A1 | |
| SCHEMBL14053938 | 0.81 | PPARG (0.38) | RORCMAPTTP53CCR9PPARG | |
| SCHEMBL14053566 | 0.80 | PPARG (0.39) | RORCPPARGPPARAPPARD | |
| SCHEMBL14058394 | 0.80 | PPARG (0.38) | RORCMAPTTP53PPARGPPARA | |
| SCHEMBL14054058 | 0.80 | PPARG (0.38) | RORCMAPTTP53PPARGPPARA | |
| SCHEMBL14054024 | 0.79 | PPARG (0.40) | RORCCCR9PPARGPPARAPPARD | |
| SCHEMBL15520693 | 0.77 | PPARG (0.41) | RORCMAPTTP53PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521727-B1 | NEW BENZOIC PYRROLOPYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARKINSON'S DISEASE | INVENTIVA (FR) | 2014-03-19 | — | — | EP | disclosed |