Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.49 |
| ▸ | KDM5A | P29375 | 4/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15519476 | 0.86 | AR (0.41) | HCAR2KDM5AKDM4CKDM5BKDM4A | |
| SCHEMBL15522023 | 0.81 | HCAR2 (0.41) | HCAR2KDM5AKDM4CKDM5BKDM4A | |
| SCHEMBL13933900 | 0.81 | HCRTR1 (0.40) | HCAR2KDM5AKDM4CKDM5BHCRTR1 | |
| SCHEMBL15520488 | 0.80 | HCAR2 (0.37) | HCAR2KDM5AKDM4CKDM5BKDM4A | |
| SCHEMBL15603543 | 0.80 | KDM5A (0.40) | HCAR2KDM5AKDM4CKDM5BKDM4A | |
| SCHEMBL15522331 | 0.79 | KDM5A (0.40) | HCAR2KDM5AKDM4CKDM5BKDM4A | |
| Hydrochloric Acid SCHEMBL15520216 | 0.79 | HCAR2 (0.37) | HCAR2KDM5AKDM4CKDM5BKDM4A | |
| SCHEMBL13933901 | 0.77 | GRIA1 (0.37) | HCAR2HCRTR1HCRTR2CYP2C8CYP2C9 | |
| SCHEMBL18611527 | 0.77 | GRIA1 (0.40) | HCAR2KDM5AKDM4CKDM5BHCRTR1 | |
| SCHEMBL15519024 | 0.77 | TAAR1 (0.39) | HCAR2KDM5AKDM4CKDM5BHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140081025-A1 | HETEROAROMATIC RING DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2014-03-20 | — | — | US | disclosed |
| US-20140081025-A1 | HETEROAROMATIC RING DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2014-03-20 | — | — | US | disclosed |
| US-20140081025-A1 | HETEROAROMATIC RING DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2014-03-20 | — | — | US | disclosed |
| EP-2708537-A1 | HETEROAROMATIC RING DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2014-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140081025-A1 | HETEROAROMATIC RING DERIVATIVE | HCRTR2, HCRTR1, HTT | HCAR2 53/4885KDM5A 3810/4885KDM4C 3725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.