Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 3/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 3/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15520216 | 0.98 | HCAR2 (0.37) | HCAR2HCRTR1HCRTR2GRIA1TAAR1 | |
| SCHEMBL15603543 | 0.85 | KDM5A (0.40) | HCAR2HCRTR1HCRTR2GRIA1PDE10A | |
| SCHEMBL13933900 | 0.83 | HCRTR1 (0.40) | HCAR2HCRTR1HCRTR2GRIA1KDM5A | |
| SCHEMBL18611527 | 0.81 | GRIA1 (0.40) | HCAR2HCRTR1HCRTR2GRIA1KDM5A | |
| SCHEMBL13933901 | 0.81 | GRIA1 (0.37) | HCAR2HCRTR1HCRTR2GRIA1DHFR | |
| SCHEMBL15519024 | 0.81 | TAAR1 (0.39) | HCAR2HCRTR1HCRTR2GRIA1TAAR1 | |
| Hydrochloric Acid SCHEMBL15518993 | 0.80 | TAAR1 (0.38) | HCAR2HCRTR1HCRTR2GRIA1TAAR1 | |
| SCHEMBL15519258 | 0.80 | HCAR2 (0.49) | HCAR2HCRTR1HCRTR2GRIA1KDM5A | |
| SCHEMBL15519702 | 0.79 | HCAR2 (0.36) | HCAR2HCRTR1HCRTR2GRIA1PDE10A | |
| SCHEMBL16648602 | 0.78 | GRIA1 (0.41) | HCAR2HCRTR1HCRTR2GRIA1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140081025-A1 | HETEROAROMATIC RING DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2014-03-20 | — | — | US | disclosed |
| US-20140081025-A1 | HETEROAROMATIC RING DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2014-03-20 | — | — | US | disclosed |
| EP-2708537-A1 | HETEROAROMATIC RING DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2014-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140081025-A1 | HETEROAROMATIC RING DERIVATIVE | HCRTR2, HCRTR1, HTT | HCAR2 53/4885HCRTR1 2/4885HCRTR2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.