SCHEMBL15519266

SCHEMBL15519266

OCC(Cl)COCC(O)CCl

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
AR P10275 1/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 1/20 0.33
USP2 O75604 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15519224 0.86 USP2 (0.42) TP53TSHRTDP1USP2KDM4E
SCHEMBL5324603 0.83 AR (0.44) TP53TSHRTDP1ARCA1
SCHEMBL202567 0.83 CA1 (0.45) TSHRARCA1CA2CA9
SCHEMBL7037851 0.83 TP53 (0.47) TP53TSHRTDP1
SCHEMBL5360236 0.81 AR (0.43) TP53TSHRTDP1ARCA1
Ethylene Glycol SCHEMBL7535155 0.80 CA1 (0.39) TSHRARCA1CA2CA9
SCHEMBL811510 0.80 CA1 (0.43) TSHRARCA1CA2CA9
SCHEMBL19951506 0.80 CA1 (0.43) TSHRARCA1CA2CA9
SCHEMBL9295062 0.76 CA1 (0.36) TP53TSHRTDP1CA1CA2
Di(Hydroxyethyl)Ether SCHEMBL9447831 0.74 TSHR (0.48) TSHRARCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2895449-A1 PROCESS OF STRIPPING A LIQUID MEDIUM Solvay SA (BE) 2015-07-22 EP claimed
WO-2014040883-A1 PROCESS OF STRIPPING A LIQUID MEDIUM SOLVAY SA (BE) 2014-03-20 WO claimed
EP-2895449-A1 PROCESS OF STRIPPING A LIQUID MEDIUM Solvay SA (BE) 2015-07-22 EP disclosed
WO-2014040883-A1 PROCESS OF STRIPPING A LIQUID MEDIUM SOLVAY SA (BE) 2014-03-20 WO disclosed
EP-2708525-A1 Process of stripping a liquid medium Solvay SA (BE) 2014-03-19 EP disclosed