Ethylene Glycol

Ethylene Glycol

SCHEMBL7535155

OC(CCl)COCC(O)CCl.OCCO

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 1/20 0.39
KDM4E B2RXH2 1/20 0.36
AR P10275 1/20 0.34
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
USP2 O75604 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202567 0.91 CA1 (0.45) CA1CA2CA9KDM4EAR
SCHEMBL811510 0.88 CA1 (0.43) CA1CA2CA9KDM4EAR
SCHEMBL19951506 0.88 CA1 (0.43) CA1CA2CA9KDM4EAR
Di(Hydroxyethyl)Ether SCHEMBL9447831 0.87 TSHR (0.48) CA1CA2CA9KDM4EAR
SCHEMBL5324603 0.86 AR (0.44) CA1CA2CA9KDM4EAR
Triethylene Glycol SCHEMBL9447827 0.85 MEN1 (0.50) CA1CA2CA9KDM4EAR
SCHEMBL5360236 0.84 AR (0.43) CA1CA2CA9KDM4EAR
SCHEMBL5021528 0.84
SCHEMBL15519266 0.80 TP53 (0.46) CA1CA2CA9KDM4EAR
SCHEMBL7535158 0.80 CA1 (0.41) CA1CA2CA9KDM4EAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002038371-A METHOD FOR PREVENTING FIBRILLATION OF CELLULOSE FIBER IPPOSHA OIL IND CO LTD 2002-02-06 JP disclosed
US-5224963-A Improving perspiration fastness BASF AKTIENGESELLSCHAFT (DE) 1993-07-06 US disclosed
US-5015754-A Cationic polyethers for fixing reative and direct dyes used for dyeing and printing cellulose textiles; washfastness BASF AKTIENGESELLSCHAFT (DE) 1991-05-14 US disclosed