SCHEMBL15519453

SCHEMBL15519453

OCC(O)COC(CO)CCl

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
ALDH1A1 P00352 1/20 0.36
AR P10275 1/20 0.35
USP2 O75604 1/20 0.32
THRB P10828 1/20 0.31
TP53 P04637 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15519293 0.91 AR (0.35) LMNAALDH1A1ARTP53TSHR
SCHEMBL882914 0.85 LMNA (0.44) LMNAALDH1A1USP2THRBTSHR
SCHEMBL15519342 0.83 CA1 (0.36) LMNAALDH1A1ARTP53TSHR
SCHEMBL15827409 0.81 SMN1; SMN2 (0.34) ALDH1A1ARUSP2TSHR
SCHEMBL14481872 0.78 LMNA (0.38) LMNAALDH1A1USP2THRB
SCHEMBL14478629 0.78 LMNA (0.38) LMNAALDH1A1USP2THRB
SCHEMBL16134391 0.78 USP2 (0.42) LMNAALDH1A1USP2THRB
SCHEMBL10957305 0.77 CA1 (0.39) ALDH1A1ARTSHR
SCHEMBL12386550 0.76 LMNA (0.39) LMNAALDH1A1THRBTDP1
SCHEMBL532450 0.76 LMNA (0.48) LMNAALDH1A1USP2THRBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2895449-A1 PROCESS OF STRIPPING A LIQUID MEDIUM Solvay SA (BE) 2015-07-22 EP claimed
WO-2014040883-A1 PROCESS OF STRIPPING A LIQUID MEDIUM SOLVAY SA (BE) 2014-03-20 WO claimed
EP-2895449-A1 PROCESS OF STRIPPING A LIQUID MEDIUM Solvay SA (BE) 2015-07-22 EP disclosed
WO-2014040883-A1 PROCESS OF STRIPPING A LIQUID MEDIUM SOLVAY SA (BE) 2014-03-20 WO disclosed
EP-2708525-A1 Process of stripping a liquid medium Solvay SA (BE) 2014-03-19 EP disclosed