Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15520312 | 0.92 | CHEK1 (0.50) | CHEK1 | |
| SCHEMBL15520721 | 0.92 | CHEK1 (0.43) | CHEK1 | |
| SCHEMBL15520202 | 0.89 | CHEK1 (0.38) | CHEK1 | |
| SCHEMBL15520746 | 0.89 | CHEK1 (0.38) | CHEK1 | |
| SCHEMBL15520361 | 0.89 | CHEK1 (0.38) | CHEK1 | |
| SCHEMBL950529 | 0.88 | CHEK1 (0.51) | CHEK1CDK7 | |
| SCHEMBL15520771 | 0.88 | CHEK1 (0.36) | CHEK1 | |
| SCHEMBL15520814 | 0.88 | KDR (0.39) | CHEK1 | |
| SCHEMBL949819 | 0.87 | CHEK1 (0.49) | CHEK1CDK7 | |
| SCHEMBL15520680 | 0.87 | KDR (0.38) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2294065-B1 | INDOLYL-PYRIDONE DERIVATIVES HAVING CHECKPOINT KINASE 1 INHIBITORY ACTIVITY | VERNALIS R&D LTD (GB) | 2014-03-19 | — | — | EP | claimed |