Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 2/20 | 0.39 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15615142 | 0.94 | AGPAT2 (0.39) | AGPAT2CEPT1MCHR1THRATHRB | |
| SCHEMBL15522352 | 0.83 | AGPAT2 (0.40) | AGPAT2CEPT1MCHR1THRATHRB | |
| SCHEMBL15522294 | 0.79 | TP53 (0.37) | AGPAT2CEPT1THRBF2RL3TP53 | |
| SCHEMBL15615127 | 0.77 | TP53 (0.36) | AGPAT2CEPT1THRBF2RL3TP53 | |
| SCHEMBL31078471 | 0.72 | LMNA (0.44) | GAATDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL26103495 | 0.72 | LMNA (0.44) | GAATDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL18901651 | 0.72 | LMNA (0.44) | GAATDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL278733 | 0.72 | LMNA (0.44) | GAATDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL3628620 | 0.72 | LMNA (0.44) | GAATDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL28421317 | 0.71 | LMNA (0.46) | THRBGAATDP1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9845318-B2 | Class of near infrared optical probes for biological applications | THE UNIVERSITY OF AKRON (US) | 2017-12-19 | — | — | US | disclosed |
| US-9090602-B2 | Class of near infrared optical probes for biological applications | THE UNIVERSITY OF AKRON (US) | 2015-07-28 | — | — | US | disclosed |
| US-20150148631-A1 | CLASS OF NEAR INFRARED OPTICAL PROBES FOR BIOLOGICAL APPLICATIONS | THE UNIVERSITY OF AKRON | 2015-05-28 | — | — | US | disclosed |
| US-20140080168-A1 | CLASS OF NEAR INFRARED OPTICAL PROBES FOR BIOLOGICAL APPLICATIONS | THE UNIVERSITY OF AKRON (US) | 2014-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140080168-A1 | CLASS OF NEAR INFRARED OPTICAL PROBES FOR BIOLOGICAL APPLICATIONS | ZKSCAN2, ZRANB2, ZFX | AGPAT2 4573/4885CEPT1 3900/4885MCHR1 3231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.