SCHEMBL15524696

SCHEMBL15524696

O=C(O)c1cc(O)cc(I)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.47
CA12 O43570 3/20 0.45
CA1 P00915 3/20 0.45
CA2 P00918 3/20 0.45
CA7 P43166 3/20 0.45
CA9 Q16790 3/20 0.45
CA14 Q9ULX7 3/20 0.45
ALOX5 P09917 1/20 0.45
PTGS2 P35354 1/20 0.45
TP53 P04637 1/20 0.44
AKR1C4 P17516 2/20 0.42
AKR1C3 P42330 2/20 0.42
AKR1C2 P52895 2/20 0.42
AKR1C1 Q04828 2/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
HTT P42858 2/20 0.41
PDE4A P27815 1/20 0.41
BLVRB P30043 1/20 0.41
KDR P35968 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL686599 0.83 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL29396210 0.82 TTR (0.56) TTRTP53AKR1C4AKR1C3AKR1C2
SCHEMBL425350 0.82 TTR (0.56) TTRTP53AKR1C4AKR1C3AKR1C2
Lithium SCHEMBL30311136 0.80 TTR (0.54) TTRTP53AKR1C4AKR1C3AKR1C2
SCHEMBL9398438 0.80 TTR (0.54) TTRTP53AKR1C4AKR1C3AKR1C2
SCHEMBL23803707 0.80 TTR (0.54) TTRTP53AKR1C4AKR1C3AKR1C2
SCHEMBL340511 0.80 TTR (0.54) TTRTP53AKR1C4AKR1C3AKR1C2
Lithium SCHEMBL410866 0.80 TTR (0.54) TTRTP53AKR1C4AKR1C3AKR1C2
SCHEMBL9403722 0.80 TTR (0.54) TTRTP53AKR1C4AKR1C3AKR1C2
SCHEMBL27960207 0.80 TTR (0.54) TTRTP53AKR1C4AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9079989-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-07-14 US disclosed
US-20150025213-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-01-22 US disclosed
US-8883946-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-11-11 US disclosed
US-20140080989-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-03-20 US disclosed