Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | AOC2 | O75106 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15527151 | 1.00 | MAOB (0.52) | MAOBAOC3SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL16767233 | 0.85 | MAOB (0.47) | MAOBAOC3SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL16767234 | 0.85 | MAOB (0.47) | MAOBAOC3SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL16787368 | 0.83 | MAOB (0.58) | MAOBAOC3SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL16767243 | 0.82 | AOC3 (0.64) | MAOBAOC3AOC2MAOADAO | |
| SCHEMBL16767516 | 0.82 | AOC3 (0.64) | MAOBAOC3AOC2MAOADAO | |
| SCHEMBL16767244 | 0.82 | AOC3 (0.64) | MAOBAOC3AOC2MAOADAO | |
| Hydrochloric Acid SCHEMBL15527460 | 0.81 | AOC3 (0.64) | MAOBAOC3AOC2MAOADAO | |
| Hydrochloric Acid SCHEMBL15527462 | 0.81 | AOC3 (0.64) | MAOBAOC3AOC2MAOADAO | |
| Hydrochloric Acid SCHEMBL16766591 | 0.81 | AOC3 (0.64) | MAOBAOC3AOC2MAOADAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107266332-B | Substituted 3-haloallylamine inhibitors of SSAO and uses thereof | 勃林格殷格翰国际有限公司 | 2020-07-24 | — | — | CN | disclosed |
| EP-2844637-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF SSAO AND USES THEREOF | PharmAxis Ltd (AU) | 2015-03-11 | — | — | EP | disclosed |
| WO-2013163675-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF SSAO AND USES THEREOF | PHARMAXIS LTD. (AU) | 2013-11-07 | — | — | WO | disclosed |