Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.58 |
| ▸ | AOC3 | Q16853 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | AOC2 | O75106 | 6/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | DAO | P14920 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18026502 | 0.89 | AOC3 (0.49) | MAOBAOC3ALDH1A1AOC2MAOA | |
| SCHEMBL16767243 | 0.87 | AOC3 (0.64) | MAOBAOC3AOC2MAOADAO | |
| SCHEMBL18026493 | 0.87 | ALDH1A1 (0.53) | MAOBAOC3ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL16767244 | 0.87 | AOC3 (0.64) | MAOBAOC3AOC2MAOADAO | |
| SCHEMBL16767516 | 0.87 | AOC3 (0.64) | MAOBAOC3AOC2MAOADAO | |
| Hydrochloric Acid SCHEMBL15527460 | 0.86 | AOC3 (0.64) | MAOBAOC3AOC2MAOADAO | |
| Hydrochloric Acid SCHEMBL15527462 | 0.86 | AOC3 (0.64) | MAOBAOC3AOC2MAOADAO | |
| Hydrochloric Acid SCHEMBL16766591 | 0.86 | AOC3 (0.64) | MAOBAOC3AOC2MAOADAO | |
| SCHEMBL18026499 | 0.84 | AOC3 (0.46) | MAOBAOC3AOC2MAOADAO | |
| SCHEMBL15527151 | 0.83 | MAOB (0.52) | MAOBAOC3ALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086698-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF SSAO AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2018-03-29 | — | — | US | disclosed |
| US-9815782-B2 | Substituted 3-haloallylamine inhibitors of SSAO and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| US-20160244406-A1 | Substituted 3-Haloallylamine Inhibitors of SSAO and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-08-25 | — | — | US | disclosed |
| US-9302986-B2 | Substituted 3-haloallylamine inhibitors of ASSAO and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-04-05 | — | — | US | disclosed |
| US-20150158813-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF ASSAO AND USES THEREOF | PHARMAXIS, LTD. (AU) | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244406-A1 | Substituted 3-Haloallylamine Inhibitors of SSAO and uses thereof | AOC3, HAO1, VAPA | MAOB 212/4885AOC3 1/4885ALDH1A1 33/4885 |
| US-20180086698-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF SSAO AND USES THEREOF | AOC3, HAO1, VAPA | MAOB 212/4885AOC3 1/4885ALDH1A1 33/4885 |
| US-20150158813-A1 | SUBSTITUTED 3-HALOALLYLAMINE INHIBITORS OF ASSAO AND USES THEREOF | HAO1, VAPA, AOC3 | MAOB 524/4885AOC3 3/4885ALDH1A1 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.