Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553038 | 0.91 | CHEK2 (0.69) | CHEK2 | |
| SCHEMBL1553024 | 0.91 | CHEK2 (0.69) | CHEK2 | |
| SCHEMBL1551653 | 0.90 | CHEK2 (0.70) | CHEK2DHODH | |
| SCHEMBL1552688 | 0.89 | CHEK2 (0.71) | CHEK2 | |
| SCHEMBL5176542 | 0.88 | CHEK2 (0.53) | CHEK2DHODH | |
| SCHEMBL1551742 | 0.88 | CHEK2 (0.85) | CHEK2 | |
| SCHEMBL1552345 | 0.87 | CHEK2 (0.72) | CHEK2 | |
| SCHEMBL1553042 | 0.86 | CHEK2 (0.67) | CHEK2 | |
| SCHEMBL5179213 | 0.84 | CHEK2 (0.57) | CHEK2 | |
| SCHEMBL1553015 | 0.84 | CHEK2 (0.76) | CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824832-B1 | ARYL-SUBSTITUTED BENZIMIDAZOLE AND IMIDAZOPYRIDINE ETHERS AS ANTI-CANCER AGENTS | JANSSEN PHARMACEUTICA NV (BE) | 2011-04-27 | — | — | EP | claimed |