Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15364824 | 0.80 | ALDH1A1 (0.34) | CES2CES1HTTTSHRMAPK1 | |
| SCHEMBL15527619 | 0.74 | KDM1A (0.39) | KDM1AHTTTSHRUSP2SMN1; SMN2 | |
| SCHEMBL15527711 | 0.73 | HPGD (0.41) | KDM1AHTTUSP2SMN1; SMN2 | |
| SCHEMBL15527450 | 0.73 | KDM1A (0.42) | KDM1ACES2CES1DEGS1TSHR | |
| SCHEMBL15364416 | 0.72 | ESR1 (0.39) | CES2CES1HTTTSHRSMN1; SMN2 | |
| SCHEMBL15527332 | 0.69 | KDM1A (0.40) | KDM1ACES2CES1DEGS1TSHR | |
| SCHEMBL15527844 | 0.68 | KDM1A (0.39) | KDM1ACES2CES1DEGS1TSHR | |
| SCHEMBL15527470 | 0.68 | KDM1A (0.39) | KDM1ACES2CES1HTTDEGS1 | |
| SCHEMBL15364667 | 0.67 | TSHR (0.44) | KDM1AHTTTSHRUSP2SMN1; SMN2 | |
| SCHEMBL23458124 | 0.67 | KDM1A (0.48) | KDM1ACES2CES1DEGS1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2844678-A1 | POLYDIENES AND DIENE COPOLYMERS HAVING ORGANOPHOSPHINE FUNCTIONALITY | Bridgestone Corporation (JP) | 2015-03-11 | — | — | EP | disclosed |
| WO-2013166124-A1 | POLYDIENES AND DIENE COPOLYMERS HAVING ORGANOPHOSPHINE FUNCTIONALITY | BRIDGESTONE CORPORATION (JP) | 2013-11-07 | — | — | WO | disclosed |