Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4901578 | 0.83 | TSHR (0.54) | HPGDHSD17B10KDM4EALDH1A1ALOX15 | |
| Salsalate SCHEMBL29362887 | 0.82 | HSD17B10 (1.00) | HPGDHSD17B10KDM4EALDH1A1ALOX15 | |
| Salsalate SCHEMBL15562 | 0.82 | HSD17B10 (1.00) | HPGDHSD17B10KDM4EALDH1A1ALOX15 | |
| Salsalate SCHEMBL2025628 | 0.82 | HSD17B10 (1.00) | HPGDHSD17B10KDM4EALDH1A1ALOX15 | |
| SCHEMBL8092427 | 0.82 | HSD17B10 (0.64) | HPGDHSD17B10KDM4EALDH1A1ALOX15 | |
| SCHEMBL16674880 | 0.81 | HSD17B10 (0.63) | HPGDHSD17B10KDM4EALDH1A1ALOX15 | |
| SCHEMBL9333909 | 0.81 | HSD17B10 (0.63) | HPGDHSD17B10KDM4EALDH1A1ALOX15 | |
| Salsalate SCHEMBL25177171 | 0.81 | KDM4E (0.96) | HPGDHSD17B10KDM4EALDH1A1ALOX15 | |
| Salsalate SCHEMBL9704557 | 0.81 | HSD17B10 (0.96) | HPGDHSD17B10KDM4EALDH1A1ALOX15 | |
| Salsalate SCHEMBL9624915 | 0.81 | HSD17B10 (0.96) | HPGDHSD17B10KDM4EALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2847563-A2 | DUAL-FUNCTION HEAT INDICATOR AND METHOD OF MANUFACTURE | Temptime Corporation (US) | 2015-03-18 | — | — | EP | claimed |
| WO-2013170273-A2 | DUAL-FUNCTION HEAT INDICATOR AND METHOD OF MANUFACTURE | TEMPTIME CORPORATION (US) | 2013-11-14 | — | — | WO | claimed |